DNA Damage and Tissue Repair: What We Can Learn …
Planaria have abundant SCs (neoblasts) that maintain high rates of cellular turnover and a variety of molecular tools have been developed to induce DNA damage and dissect how neoblasts respond to this stressor. S. mediterranea …
Planarians: A Versatile and Powerful Model System for Molecular …
This article provides an overview of the planarian model system with special attention to the species Schmidtea mediterranea. Additionally, information is provided about the most popular …
Not your father's planarian: a classic model enters the …
2002年3月1日 · The tremendous strides made in understanding embryogenesis have been driven largely by genetic approaches using model systems that are …
- 作者: Phillip A. Newmark, Alejandro Sánchez Alvarado
- Publish Year: 2002
A comparative analysis of planarian genomes reveals regulatory ...
2024年9月19日 · Using hybrid gene annotations and optimized ATAC-seq and ChIP-seq protocols for regulatory element annotation, we provide valuable genome resources for the planarian …
Are Planaria Individuals? What Regenerative Biology is ... - Springer
2018年3月12日 · We review molecular and developmental evidence suggesting that mature intact planaria are not biological individuals but their totipotent stem cells (neoblasts) are individuals. …
- 作者: Chris Fields, Michael Levin
- 预计阅读时间：13 分钟
- Publish Year: 2018
A planarian’s guide to growing a new head | Whitehead Institute
2025年2月6日 · In their latest study, published in PLOS Genetics on February 6, first author staff scientist M. Lucila Scimone, Reddien, and colleagues describe how planarians restore large …
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Stem cell systems and regeneration in planaria - PMC
Planarians are members of the Platyhelminthes (flatworms). These animals have evolved a remarkable stem cell system. A single pluripotent adult stem cell type (“neoblast”) gives rise to …
Model systems for regeneration: planarians
2019年9月11日 · Planarians are a group of flatworms. Some planarian species have remarkable regenerative abilities, which involve abundant pluripotent adult stem cells. This makes these worms a powerful model system for …
The Cellular and Molecular Basis for Planarian …
Much excellent and fascinating work on planarian biology will not be reviewed here, such as the role of myriad molecules that give planarian stem cells (neoblasts) their attributes, the molecular genetics of the planarian germline, …
Regeneration and gene regulation in planarians - ScienceDirect
2003年10月1日 · A planarian can regenerate entirely from just a small body fragment. This ability has been considered to reside in pluripotent stem cells, which can give rise to all missing cell …
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