Dec 25, 2024 · GBP1 (Guanylate Binding Protein 1) is a Protein Coding gene. Diseases associated with GBP1 include Ulceroglandular Tularemia and Kaposi Sarcoma. Among its …

Interferon-induced guanylate-binding protein 1 is a protein that in humans is encoded by the GBP1 gene. [3][4] It belongs to the dynamin superfamily of large GTPases. [5] Guanylate …

GBP1, the most widely studied GBP, has been studied for its antimicrobial properties. It can effectively polymerize and target the lipopolysaccharide cell wall of gram-negative bacteria.

Feb 22, 2022 · GBP1 identifies gram-negative bacteria such as the enteric pathogen, Salmonella enterica serovar Typhimurium, that enter the cytoplasm of the host cell. GBP1 then quickly …

Jul 1, 2019 · GBP1 thus acts as a gatekeeper of cell death pathways, which respond specifically to infecting microbes. Our findings expand the immune roles of human GBPs in regulating not …

Jun 30, 2022 · GBP1 is a 65-kD GTPase protein in the GBP family that plays a crucial role in innate immunity 14, comprising a conserved region with an N-terminal globular GTPase …

Jan 24, 2020 · Guanylate-binding protein 1 (GBP1) is a large GTPase of the dynamin superfamily involved in the regulation of membrane, cytoskeleton, and cell cycle progression dynamics.

Aug 16, 2020 · Guanylate binding protein 1 (GBP-1) promotes cell motility and invasiveness of lung adenocarcinoma. Yamakita I, et al. Biochem Biophys Res Commun, 2019 Oct 15. PMID …

Jul 29, 2022 · Here, we show that guanylate-binding proteins (GBPs) mediate pathogen-selective inflammasome activation. We show that mouse GBP1 and GBP3 are specifically required for …

Mar 5, 2021 · GBP1 represses the genomic transcription of VSV by competitively binding to the VSV-N substituting for the VSV-P, inhibits the nuclear delivery of KSHV virions by disrupting …

Our results identify human GBP1 as the principal repetitive unit, numbering thousands of proteins per bacillus, that undergoes dramatic conformational opening to establish a host defense …

Guanylate-binding protein 1 (GBP1) is a large GTPase of the dynamin superfamily involved in the regulation of membrane, cytoskeleton, and cell cycle progression dynamics. In many cell …

Jan 2, 2024 · Guanylate binding protein 1 (GBP1) is the most concerned member of the GBP family, which has a series of effects such as anti-infection and anti-angiogenesis. Its role in …

Interferon-gamma-induced GBP1 is an inhibitor of human papillomavirus 18. Guanylate-binding protein 1 acts as a pro-viral factor for the life cycle of hepatitis C virus. Function and …

Feb 18, 2022 · Scientists recently made a significant breakthrough in the recognition of pathogens via guanylate binding protein 1 (GBP1). Wandel et al. [1] in Nature Immunology described their …

Jun 24, 2024 · Guanylate-binding protein 1 (GBP1) is one of the interferon-stimulating factors, which participates in the innate immunity of the host and plays an antiviral and antibacterial …

Oct 15, 2024 · Using cryo-electron microscopy (cryo-EM), cryo-electron tomography (cryo-ET) and biophysical assays, we show how GBP1 oligomers enwrap and remodel the …

Jan 23, 2020 · Guanylate-binding protein 1 (GBP1) is a large GTPase of the dynamin superfamily involved in the regulation of membrane, cytoskeleton, and cell cycle progression dynamics.

Jul 1, 2019 · GBP 1 facilitated caspase‐4 recruitment to Salmonella leading to its enhanced activation and pyroptosis. Notably, GBP 1 could be bypassed by the delivery of Toxoplasma …

Nov 17, 2023 · Guanylate-binding protein 1 (GBP1) is known as an interferon-γ-induced GTPase. Here, we used genetically modified ovarian cancer (OC) cells to study the role of GBP1. The …

1 day ago · GBP1.062500bln had been on offer.This leaves GBP18.944bln of the gilt in issue. GILT PAOF RESULTS: GBP1.062499bln of the 4.375% Mar-28 Gilt sold. - Bonds & Currency …

1 day ago · (Alliance News) - Hedge fund manager Crispin Odey has been fined GBP1.8 million and banned from the UK finance industry for a "lack of integrity", the financial watchdog has …