
GATA2 - Wikipedia
GATA2 or GATA-binding factor 2 is a transcription factor, i.e. a nuclear protein which regulates the expression of genes. [5] . It regulates many genes that are critical for the embryonic …
GATA2deficiency is a rare disorder of the immune system with wide-ranging effects. First identified in 2011, the disorder is char. - acterized by immunodeficiency, myelodys- plastic …
The Clinical Spectrum, Diagnosis, and Management of GATA2 …
In this review, we will examine the structural characteristics of the GATA2 gene, its physiological and pathological functions, how GATA2 genetic mutations contribute to myeloid neoplasms, …
GATA2 deficiency - Wikipedia
GATA2 deficiency is a grouping of several disorders caused by common defect, namely, familial or sporadic inactivating mutations in one of the two parental GATA2 genes. Because the gene …
The spectrum of GATA2 deficiency syndrome
2023年3月30日 · Inherited or de novo germ line heterozygous mutations in the gene encoding the transcription factor GATA2 lead to its deficiency. This results in a constellation of clinical …
GATA2 Gene - GeneCards | GATA2 Protein | GATA2 Antibody
2024年12月25日 · GATA2 (GATA Binding Protein 2) is a Protein Coding gene. Diseases associated with GATA2 include Immunodeficiency 21 and Myelodysplastic Syndrome. Among …
GATA2 deficiency syndrome: A decade of discovery - PubMed
GATA2 deficiency syndrome (G2DS) is a rare autosomal dominant genetic disease predisposing to a range of symptoms, of which myeloid malignancy and immunodeficiency including …
GATA2 Deficiency Syndrome (PDQ®) - NCI - National Cancer …
2024年8月22日 · GATA2 deficiency syndrome is a hereditary hematologic malignancy syndrome associated with the GATA2 gene. Learn about GATA2's clinical features and management.
GATA 2 Deficiency: Focus on Immune System Impairment - PMC
GATA2 deficiency is a disease with a broad spectrum of clinical presentation, ranging from lymphedema, deafness, pulmonary dysfunction to miscarriage and urogenital anomalies, but it …
Role of the pioneer transcription factor GATA2 in health and disease
2023年8月25日 · GATA2 is one of six GATA-family transcription factors that act as pioneering transcription factors which facilitate the opening of heterochromatin and the subsequent …