2024年12月25日 · GABRA6 (Gamma-Aminobutyric Acid Type A Receptor Subunit Alpha6) is a Protein Coding gene. Diseases associated with GABRA6 include Ovarian Cancer and …

Gamma-aminobutyric acid receptor subunit alpha-6 is a protein that in humans is encoded by the GABRA6 gene. [5] [6] GABA is the major inhibitory neurotransmitter in the mammalian brain …

2024年12月15日 · 该研究表明,创伤性脑损伤和应激源在PTSD的发展中是独立的组成部分,Gabra6神经元在协同促进PTSD的形成中起关键作用。 减少单一或复合压力源暴露的策略可 …

GABRA6 mutation, R46W, was identified as a susceptibility gene that may contribute to the pathogenesis of childhood absence epilepsy and cause neuronal disinhibition and increase in …

2007年2月20日 · Alpha-6/GABRA6 subunits are found at both synaptic and extrasynaptic sites (PubMed:8632757). Chloride influx into the postsynaptic neuron following GABAAR opening …

2025年2月8日 · Enables transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential. Predicted to be involved in several processes, including …

2025年1月4日 · We tested the hypothesis that homocysteine (Hcy) antagonizes the GABA (A) receptor and behaves as an excitotoxic neurotransmitter that causes blood brain barrier (BBB) …

GABRA6, the gene that codes for GABRα6 subunit, is located at 5q31.1–q35 (Hicks et al., 1994) and is another member of the extrasynaptic GABAA receptors (Wafford, 2014). From: …

GABA 是哺乳动物大脑中的主要抑制性神经递质，它作用于 GABA-A 受体，即配体门控氯离子通道。 这些通道的氯离子电导可以通过与 GABA-A 受体结合的药物 (例如苯二氮卓类药物) 进行调 …

伽马氨基丁酸（GABA）是哺乳动物大脑中的主要抑制性神经递质，它在伽马氨基丁酸A受体上发挥作用，这些受体是配体门控的氯离子通道。 这些通道的氯离子传导可以被结合到伽马氨基丁 …