2024年12月25日 · GSTP1 (Glutathione S-Transferase Pi 1) is a Protein Coding gene. Diseases associated with GSTP1 include Kala-Azar 2 and Hepatocellular Adenoma. Among its related …

This GST family member is a polymorphic gene encoding active, functionally different GSTP1 variant proteins that are thought to function in xenobiotic metabolism and play a role in …

Glutathione S-transferase Pi 1 (GSTP1) is an enzyme with an important antioxidant role and is encoded for by the GSTP1 gene. Glutathione is an important antioxidant molecule which …

The GSTP1 gene, encoding the pi class glutathione S-transferase, was the first hypermethylated gene to be characterized in prostate cancer. GSTP1 is thought to protect prostate epithelial …

Glutathione transferase P1-1 (GSTP1-1) is expressed in some human tissues and is abundant in mammalian erythrocytes (here termed e-GST). This enzyme is able to detoxify the cell from …

2019年1月25日 · In the current study, we found a novel mechanism by which GSTP1 protects human breast cancer cells from adriamycin (ADR)-induced cell death and contributes to the …

The glutathione S-transferase P1 (GSTP1) is involved in multiple cellular functions, including phase II metabolism, stress response, signaling, and apoptosis. The mechanisms underlying …

2018年1月24日 · Monomeric GSTP1 protects tumoral cells from apoptosis by inhibition of the JNK signaling pathway through the formation of a GSTP1-JNK-cJun complex that hampers c-Jun …

2020年12月23日 · A stable-isotope labeling by amino acids in cell culture coupled with mass spectrometry-based proteomics identifies upregulation of glutathione S-transferase pi 1 …

The silencing of GSTP1 via promoter hypermethylation is a well-documented epigenetic alteration in several cancers, such as prostate, breast, and lung cancer (Cui et al., 2006). In HCC, the …