FOXP3 - Wikipedia
Foxp3 is a specific marker of natural T regulatory cells (nTregs, a lineage of T cells) and adaptive/induced T regulatory cells (a/iTregs), also identified by other less specific markers …
FOXP3 - 维基百科，自由的百科全书
FOXP3（Forkhead box protein P3）基因，即叉头框P3基因，也称为scurfin蛋白，位于X染色体，属于FOX蛋白家族，是一种与免疫系统 响应有关的转录因子 [6] 。
Forkhead box protein P3（FOXP3） - Abcam中文官网
FOXP3靶点介绍 蛋白功能 FOXP3是一种转录调控因子，对调节性T细胞（Treg）的发育和抑制功能至关重要。 FOXP3通过调节Treg的稳定性和抑制功能，以及直接调节常规T细胞的扩增和 …
The regulation of immune tolerance by FOXP3 - Nature
Jul 31, 2017 · This Review considers how forkhead box protein P3 (FOXP3) — the key transcription factor of regulatory T (Treg) cells — is regulated both at the transcriptional level …
Foxp3: Treg的主要调节因子 - 丁香通研选
Dec 3, 2014 · 实验表明，在体外或体内诱导初始T细胞表达FoxP3后可以出现Treg样的免疫抑制作用，表明Foxp3是控制免疫抑制分子表达的关键因素；因此，阐明Foxp3的分子靶点是透彻理 …
FOXP3 and its role in the immune system - PubMed
FOXP3 is a member of the forkhead transcription factor family. Unlike other members, it is mainly expressed in a subset of CD4+ T-cells that play a suppressive role in the immune system. A …
FOXP3 recognizes microsatellites and bridges DNA through ...
Nov 29, 2023 · The cryo-electron microscopy structure of FOXP3 in a complex with T3G repeats reveals a ladder-like architecture, whereby two double-stranded DNA molecules form the two …
FOXP3 Gene - GeneCards | FOXP3 Protein | FOXP3 Antibody
Dec 25, 2024 · FOXP3 (Forkhead Box P3) is a Protein Coding gene. Diseases associated with FOXP3 include Immunodysregulation, Polyendocrinopathy, And Enteropathy, X-Linked and …
Nat Comm | Treg染色质结构塑造者Foxp3有望成为免疫治疗新靶 …
Nov 10, 2023 · 研究结果表明，Foxp3除了充当基因开关外，还负责监督调节性T细胞内更大的基因结构变化。Foxp3的存在协调了染色质结构的变化，进而指导维和免疫细胞的功能成功。作者 …
Foxp3+调节性T细胞分化发育及其功能稳定性研究进展
Foxp3+调节性T细胞（Foxp3+Treg）是一类能抑制免疫系统攻击机体自身组织的一类CD4+T细胞亚群，其关键性表型特征在于表达Forkhead家族转录因子Foxp3。 Foxp3在CD4+调节性T细 …