Forkhead box protein O1 (FOXO1), also known as forkhead in rhabdomyosarcoma (FKHR), is a protein that in humans is encoded by the FOXO1 gene. [5] FOXO1 is a transcription factor that …

2024年12月25日 · FOXO1 (Forkhead Box O1) is a Protein Coding gene. Diseases associated with FOXO1 include Rhabdomyosarcoma 2 and Diffuse Large B-Cell Lymphoma. Among its …

2002年6月7日 · We now report on the role of forkhead homologue in rhabdomyosarcoma (FKHR), a recently described member of the forkhead/winged-helix transcription factor family, as a …

In this study, we examined expressions of both nonphosphorylated (FKHR) and phosphorylated forms (p-FKHR) of FKHR in a large cohort of radical prostatectomies using tissue microarray …

The forkhead transcription factor Foxo1 (previously known as Fkhr) is phosphorylated in an insulin-responsive manner by PIP 3-dependent kinases, such as Akt and Sgk (39–50). …

2003年9月17日 · It has been shown that FKHR is phosphorylated via insulin or growth factor signaling cascades, resulting in its cytoplasmic retention and the repression of target gene …

FOXO transcription factors regulate cellular homeostasis, longevity and response to stress. FOXO1 (also known as FKHR) is a key regulator of hepatic glucose production and lipid …

1999年12月8日 · Recently, two mammalian highly related forkhead transcription factors FKHRL1 and AFX and their nematode homologue Daf-16 have been found to be targets of this kinase. …

While performing a large-scale analysis of mRNA transcripts in the murine thymus, our attention was drawn to the forkhead family transcription factor FKHR. Here we demonstrate that FKHR …

2002年6月7日 · The mammalian DAF-16-like transcription factors, FKHR, FKHRL1, and AFX, function as key regulators of insulin signaling, cell cycle progression, and apoptosis …