Cryo-EM structures of tau filaments from Alzheimer’s …
2017年7月5日 · Here we present cryo-electron microscopy (cryo-EM) maps at 3.4–3.5 Å resolution and corresponding atomic models of paired helical and …
- 作者: Anthony W. P. Fitzpatrick, Benjamin Falcon, Shaoda He, Alexey G. Murzin, Garib Murshudov, Holly J. G...
- Publish Year: 2017
Cryo-EM structures of amyloid-β and tau filaments in Down …
2024年3月29日 · The recent characterization by cryo-electron microscopy (cryo-EM) of the structure of Aβ and tau filaments in AD and related disorders 29,30,31 allows researchers to …
Cryo-EM structures of amyloid-β 42 filaments from …
2022年1月13日 · Filament assembly of amyloid-β peptides ending at residue 42 (Aβ42) is a central event in Alzheimer’s disease. Here, we report the cryo–electron microscopy (cryo-EM) structures of Aβ42 filaments fr...
Structure and assembly of ESCRT-III helical Vps24 …
2020年8月19日 · To address the open structural questions on the molecular organization of canonical ESCRT-III assemblies, we purified and enriched full …
- 作者: Stefan T. Huber, Siavash Mostafavi, Siavash Mostafavi, Simon A. Mortensen, Carsten Sachse
- Publish Year: 2020
Cryo-electron microscopy of the f1 filamentous phage reveals
2023年5月11日 · In this work, we use cryo-electron microscopy and a highly efficient system for production of short Ff-derived nanorods to determine a structure of a filamentous virus …
Cryo-electron microscopy structure of the filamentous …
2019年2月28日 · We therefore decided to elucidate a high-resolution structure of IKe using cryo-electron microscopy (cryo-EM) to explore the differences and similarities of class I phages. Here, we report an atomic model of the capsid of …
- 其他用户还问了以下问题
Cryo-EM structures of amyloid-β 42 filaments from human brains
2022年1月14日 · Filament assembly of amyloid-β peptides ending at residue 42 (Aβ42) is a central event in Alzheimer’s disease. Here, we report the cryo–electron microscopy (cryo-EM) …
Preparation of filamentous proteins for electron microscopy ...
This chapter will discuss how to overcome several major issues in cryo-EM sample preparation including construct design, screening using negative stain (ns) EM, and tips on working with …
Cryo‐EM structure of a minimal reaction center–light‐harvesting …
2025年2月6日 · Cryo-EM structure of a minimal reaction center–light-harvesting complex from the phototrophic ... (chlorosomes) makes the phototrophic bacterium Chloroflexus (Cfx.) …
Assembly of recombinant tau into filaments identical to those of ...
2022年3月4日 · Abundant filamentous inclusions of tau are characteristic of more than 20 neurodegenerative diseases that are collectively termed tauopathies. Electron cryo …
