Mar 20, 2024 · High-resolution single-cell atlas reveals diversity and plasticity of tissue-resident neutrophils in nonsmall cell lung cancer | Cancer cell (IF=50.3) 中性粒细胞marker： FCGR3B, CSF3R, CXCR2, G0S2. 3. Single cell transcriptomics of human and mouse lung cancers reveals conserved myeloid populations across individuals and species | Immunity (IF=32.4)

Dec 25, 2024 · FCGR3B (Fc Gamma Receptor IIIb) is a Protein Coding gene. Diseases associated with FCGR3B include Neutropenia, Severe Congenital, X-Linked and Neonatal Alloimmune Neutropenia. Among its related pathways are Innate Immune System and Metabolism of proteins. Gene Ontology (GO) annotations related to this gene include IgG binding.

张泽民老师的文章里对各类细胞的注释极为详细，可以参考。 亚群细分时不必拘泥于现有分类，可以使用marker基因来对细胞群命名，后续查看这些细胞群是否有生物学意义。 禁止转载，如 …

FCGR3B (Fc fragment of IgG, low affinity IIIb, receptor), also known as CD16b (C luster of D ifferentiation 16b), is a human gene. [5] Mutations and copy-number variations in this gene have been associated to clinical cases of glomerulonephritis. [6] ^ "Human PubMed Reference:".

Feb 8, 2025 · Low copy number of the Fc-γ receptor 3B gene FCGR3B is a risk factor for primary Sjogren's syndrome. Nossent JC, et al. J Rheumatol, 2012 Nov. PMID 22942264. FCGR3B copy number variation is associated with systemic lupus erythematosus risk in Afro-Caribbeans. Molokhia M, et al. Rheumatology (Oxford), 2011 Jul. PMID 21296850, Free PMC Article.

Results showed that susceptibility to systemic lupus erythematosus was associated with the FCGR3B*01 allele, as well as with the FCGR3B*01/*01 and FCGR3B*01/*02 genotypes. FcgammaRIIIB allelic distribution was similar among pediatric Guillain …

fcgr3b 分子靶点综述. cd16是一种糖基化磷脂酰肌醇锚链的细胞膜蛋白，低亲和力fcγ 受体(fcγriii)的组成部分。包括cd16a和cd16b两种亚型，结构上略有差异。cd16表达于nk细胞(只表达在成熟nk细胞，nk前体和幼稚nk细胞不表达)、一些t淋巴细胞、中性粒细胞和巨噬细胞。

May 7, 2009 · Two genes, FCGR3A and FCGR3B, encode the two receptors of the FcγRIII family (FcγRIIIa and FcγRIIIb). FcγRIII is also considered as of low affinity; however, FcγRIIIA can bind monomeric IgG ...

Nov 24, 2021 · 最近，Mohammed Uddin 的团队及合作者在《Cell》的子刊《iScience》发表了一篇标题为“Single-cell transcriptome identifies FCGR3B upregulated subtype of alveolar macrophagesin patients with critical COVID-19” 的研究论文，该研究表明，FCGR3B可能在重症新冠肺炎患者中识别出一种特殊的MoAM亚型，这可能为筛查和预后提供一个新的生物标志物，以及一个潜在的治疗靶点。 单细胞转录组学和细胞类型鉴定. 为了鉴定与重症COVID-19相关的细 …

Jun 5, 2013 · The Fc receptor with low affinity for IgG (FCGR3, or CD16) is encoded by 2 nearly identical genes, FCGR3A and FCGR3B, resulting in tissue-specific expression of alternative membrane-anchored isoforms. FCGR3A encodes a transmembrane protein expressed on activated monocytes/macrophages, natural killer (NK) cells, and a subset of T cells.