The transporter for long-chain fatty acids in the apical side of the mature enterocyte is fatty acid transporter protein 4 (FATP4). In the human, there is a family of six homologous transporters …

2019年9月13日 · Fatty acid transport protein 4 (FATP4) is an acyl-CoA synthetase that is required for normal permeability barrier in mammalian skin. FATP4 (SLC27A4) mutations cause …

2022年6月30日 · The widely distributed FATP4 is not a direct FA transporter but plays a predominant function as an ACS. FATP4 deficiency causes ichthyosis premature syndrome in …

2004年7月5日 · SLC27A4/FATP4-mediated fatty acid uptake is associated to paramaters related to insulin resistance, which is associated with disturbed fatty acid metabolism and …

In vivo, FAT/CD36 and FATP4 are the most effective fatty acid transporters, whereas FABPpm and FAT/CD36 are key for stimulating fatty acid oxidation. Uptake of long chain fatty acids …

2001年5月30日 · FATP4 (SLC27A4) is a member of the fatty acid transport protein (FATP) family, a group of evolutionarily conserved proteins that are involved in cellular uptake and …

2021年6月15日 · FATP4 is the primary intestinal fatty acid transport protein and is thought to play a major role in dietary fatty acid uptake. It has therefore been viewed as a target to prevent or …

2001年5月30日 · FATP4 (SLC27A4) is a member of the fatty acid transport protein (FATP) family, a group of evolutionarily conserved proteins that are involved in cellular uptake and …

FATP4 is localized mainly at the endoplasmic reticulum (ER) and partially localized to peroxisomes [55, 60]. It plays a role in FA transport via ACS-activated vectorial acylation [48, …

Fatty acid transport protein (FATP) 4 is one of a family of six FATPs that facilitate long- and very long-chain fatty acid uptake. Mice lacking FATP4 are born with tight, thick skin and a defective …

2012年9月14日 · Here, we used a gain-of-function approach and established FATP1, ACSVL4/FATP4 and ACSL1 stably expressing 3T3-L1 adipocytes by retroviral transduction. …

Fatp4 (-/-);Ivl-Fatp4 (tg/+) mice and wild-type littermates displayed indistinguishable food consumption, growth, and weight gain on either low or high fat (Western) diets, with no …

FA transport protein 4 (FATP4), one member of a multigene family of FA transporters, was proposed as a major FA transporter in intestinal lipid absorption. Due to the fact that Fatp4−/− …

Fatty acid transport protein 4 (FATP4) is an integral membrane protein expressed in the plasma and internal membranes of the small intestine and adipocyte as well as in the brain, kidney, …

2001年5月30日 · FATP4 (SLC27A4) is a member of the fatty acid transport protein (FATP) family, a group of evolutionarily conserved proteins that are involved in cellular uptake and …

Fatty acid transport protein 4 (FATP4) is a fatty acyl-CoA synthetase that preferentially activates very long chain fatty acid substrates, such as C24:0, to their CoA derivatives.

Fatty acid-binding protein 4 (FABP4), also known as adipocyte FABP (A-FABP) or aP2, is mainly expressed in adipocytes and macrophages and plays an important role in the development of …

2007年7月13日 · Fatty acid transport protein 4 (FATP4) is a fatty acyl-CoA synthetase that preferentially activates very long chain fatty acid substrates, such as C24:0, to their CoA …

2025年3月3日 · Another complex consisting of PLIN5 and FATP4 79 was shown to enhance LD-mitochondria contact and increase fatty acid oxidation, however, direct evidence of fatty acid …

2022年6月1日 · FATP4 is localized mainly at the endoplasmic reticulum (ER) and partially localized to peroxisomes [55,60]. It plays a role in FA transport via ACS-activated vectorial …