2016年4月9日 · The most common tracer used for PET/CT in multiple myeloma patients is “FDG” – or more specifically 18F-FDG (fluorodeoxyglucose with the fluorine-18 isotope). However, there are other tracers that have been in­ves­ti­gated for use in multiple myeloma patients, and some of them have shown results arguably superior to FDG.

2014年5月6日 · Patienten, die ein PET-Scan bekommen, erhalten eine Injektion mit Fluorodeoxyglucose, einem radioaktiven Zuckermolekül (FDG), das sich mehr in Krebszellen als in gesunden Zellen anreichert. Der PET-Scan zeigt dann die Aktivität und die Positionen von Krebszellen in verschiedenen Körperteilen aufgrund des gemessenen Radioaktivitätsniveaus.

2014年10月3日 · The group from Bologna, Italy, has evaluated the role of FDG PET/CT in patients who underwent autologous stem cell transplantation. A negative PET scan – i.e. absence of hypermetabolic spots on the scan – was associated with a more favorable outcome.

2012年3月22日 · BT-062 Shows Activity In Patients With Advanced Myeloma (ASH 2011) [ by Melissa Cobleigh and | Jan 18, 2012 3:21 pm | 3 Comments ] The results of a small Phase 1 clinical trial demonstrate that BT-062, a new drug specifically targeting multiple myeloma cells, shows activity and is tolerable in heavily pretreated multiple myeloma patients.

2014年5月21日 · Short exposure (10 minutes) to T3 and T4 increased MAPK activity by 2.5- to 3.5-fold (P < 0.03). Pharmacologic MAPK inhibition blocked the proliferative action of T3 and T4. Antibodies to the integrin αvβ3 dimer and αv and β3 monomers (but not β1) inhibited MAPK activation and subsequent cell proliferation in response to thyroid hormone ...

2015年9月5日 · Basically, I think there are two possibilities. The first is that is that this is a new area of myeloma activity, and the second is that it's a holdover from previous activity. I really don't know whether the second is really a possibility. But if it is, they may decide to do a PET/CT, or maybe biopsy the area, to investigate it further.

2010年4月6日 · I was wondering if there is anything I can do to help fight my myeloma through diet and lifestyle. Are there certain foods I should ...

2012年2月6日 · It is thought that they may work similarly to proteasome inhibitors like Velcade (bortezomib), In this preclinical study, Viracept enhanced the anti-cancer activity of myeloma drugs Velcade and dexamethasone (Decadron) as well as the epilepsy drug -- and potential anti-cancer agent -- valproic acid (Depakote, Depakene). Viracept also slowed ...

2014年9月3日 · The Karmanos researchers conducted laboratory tests of dyclonine's activity against the so-called "RPMI8226" line of myeloma cells, which is commonly used in pre-clinical testing of potential myeloma therapies. The study involved two variants of the RPMI8226 cell line: the standard variant, and a Velcade (bortezomib)-resistant variant.

2016年2月18日 · In addition, novel types of natural compounds have been developed that efficiently modulate the activity of both the cellular and humoral compartments of immunity. MGN-3 is known as an acti­va­tor of natural killer cells, inducer of apoptosis and cytokine production, and modulator of dendritic cell maturation and differentiation in vitro.