Focal cortical dysplasia (FCD) is a congenital abnormality of brain development where the neurons in an area of the brain failed to migrate in the proper formation in utero. [1] Focal …

The electro-clinical-imaging phenotypes and surgical outcomes were better defined and validated for FCDII. Little new information was acquired on clinical, histopathological, or genetic …

2024年10月10日 · Focal cortical dysplasias (FCD) represent a heterogeneous group of disorders of cortical formation, which may demonstrate both architectural and proliferative features. They …

Focal Cortical Dysplasia (FCD) is a term used to describe a focal area of abnormal brain cell (“neuron”) organization and development. Brain cells, or “neurons” normally form into …

Focal cortical dysplasia (FCD) are histopathologically categorized in ILAE type I to III. Mild malformations of cortical development (mMCD) including those with oligodendroglial …

2010年11月19日 · The term focal cortical dysplasia (FCD) was introduced for localised malformative brain lesions in patients with epilepsy who have drug-resistant seizures. Such …

FCD Type IIIc is found adjacent to vascular malformations, whereas FCD Type IIId can be diagnosed in association with epileptogenic lesions acquired in early life (i.e., traumatic injury, …

Focal cortical dysplasia is a main cause of drug-resistant epilepsy, especially in children. Novel, personalized approaches are needed to more effectively treat FCD-related epilepsy and its …

While previous studies analyzed only small sample cohorts focusing on specific pathologies, e.g., FCD or PMG, the present study is the first comprehensive description of diagnostically …

2021年7月1日 · The histopathological hallmark of FCD 1A is an abnormal radial cortical layering with microcolumnar organization of the cortical ribbon, FCD 1B with abnormal tangential …