Fatty acid-binding protein 2 (FABP2), also known as Intestinal-type fatty acid-binding protein (I-FABP), is a protein that in humans is encoded by the FABP2 gene. [5] The intracellular fatty acid-binding proteins (FABPs) belong to a multigene family with nearly twenty identified members.

Intestinal fatty acid binding protein is associated with infarct size and cardiac function in acute heart failure following myocardial infarction. Genetic polymorphisms in FABP2, CYP2E1, and TP53 genes are potentially associated with colorectal cancer susceptibility.

2024年12月25日 · FABP2 (Fatty Acid Binding Protein 2) is a Protein Coding gene. Diseases associated with FABP2 include Maturity-Onset Diabetes Of The Young and Perinatal Necrotizing Enterocolitis. Among its related pathways are Triglyceride metabolism and …

In humans, the gene encoding intestinal fatty acid binding protein (I-FABP, also known as FABP2) is located in the q28-q31 region of chromosome 4. FABP2 mRNA encodes a 132-residue protein with an Mr. of 15,124 [37], but the size of the FABP2 protein is 14- to 15-kDa.

2025年2月8日 · Fatty acid binding protein 1 (FABP1) and fatty acid binding protein 2 (FABP2) as a link between diabetic nephropathy and subclinical atherosclerosis in children and adolescents with type 1 diabetes.

2022年7月1日 · Intestinal fatty acid binding protein, also termed FABP2 or I-FABP, is specifically expressed in the small intestine. FABP2 can traffic lipids from the intestinal lumen to enterocytes and bind superfluous fatty acids to maintain a steady pool of fatty acids in the epithelium.

The fatty acid-binding protein 2 (FABP2) is considered essential for the absorption, intracellular metabolism and/or transport of dietary long chain fatty acids. It has been demonstrated that a deletion of the FABP2 gene in mice resulted in weight gain and higher circulating triglyceride concentrations than wild type mice.

Fatty acid-binding protein 2 (FABP 2) is responsible for transport of free fatty acids in the intestinal endothelium cells. FABP2 -genetic variants might affect plasma lipid concentrations and intracellular lipid transport.

2025年2月8日 · FABPs are a family of small, highly conserved, cytoplasmic proteins that bind long-chain fatty acids and other hydrophobic ligands and participate in fatty acid uptake, transport, and metabolism. This protein functions within enterocytes, possibly to sense lipids as part of energy homeostasis.

Fatty acid-binding protein 2 (FABP2) genes play a key role in the absorption and intracellular transport of dietary long chain fatty acids. The FABP2 gene is located in the 4q28–4q31 chromosomal region, consists of ∼3.4 kbs and codes for …