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Diethyl malonate, also known as DEM, is the diethyl ester of malonic acid. It occurs naturally in grapes and strawberries as a colourless liquid with an apple-like odour, and is used in perfumes. It is also used to synthesize other compounds such as barbiturates, artificial flavourings, vitamin B 1, and vitamin B 6.

主要用于生产乙氧甲叉、巴比妥酸、烷基丙二酸二乙酯，进而合成医药如诺氟沙星、罗美沙星、氯喹、保泰松等及合成染料和颜料如苯并咪唑酮类有机颜料； 4 GB 2760-2014规定为允许使用的食用香料。 主要用于配制梨、苹果、葡萄、樱桃等水果型香精； 酰化反应：丙二酸二乙酯的酰化反应会伴随有部分水解和脱羧反应，此酰化反应可应用到β-酮酯的合成。 丙二酸二乙酯水解脱去一个酯基，然后与 苯甲酰氯 (或类似物)发生酰化反应，随后转化成喹诺酮衍生物； 与醛等的反 …

中文名:丙二酸二乙酯,英文名:Ethyl malonate,CAS:105-53-3,化学式:C7H12O4,分子量:160.17,密度:1.055 g/mL at 25 °C (lit.),熔点:-51--50 °C (lit.),沸点:199 °C (lit.),闪点:212°F,水溶性:Miscible with ethyl alcohol, ether, chloroform and benzene.

Aldrich-445088; mono-Ethyl malonate; CAS No.: 1071-46-1; Linear Formula: HO2CCH2CO2C2H5; Empirical Formula: C5H8O4; find related products, papers, technical documents, MSDS & more at Sigma-Aldrich.

丙二酸二乙酯是制备2-氨基-4，6-二甲氧基嘧啶的重要中间体，可用于制备磺酰脲类除草剂，如苄嘧磺隆、吡嘧磺隆、烟嘧磺隆等，也是医药中用于磺胺药和巴比妥的中间体。 它还可用于气相色谱固定液 (最高使用温度40℃，溶剂为苯、氯仿、乙醇)来检定氨和钾。 此外丙二酸二乙酯也是GB 2760一96规定为允许使用的食用香料，主要用于配制梨、苹果、葡萄、樱桃等水果型香精。 由丙二酸和乙醇在苯介质中共沸、蒸馏、酯化而得。 由丙二酸钠与乙醇在硫酸催化下酯化后蒸馏 …

Solubility in water: soluble. Other solubilities: soluble in other solvents. Causes skin irritation. May cause respiratory irritation. Causes serious eye irritation. Wear protective gloves/protective clothing/eye protection/face protection. If skin irritation occurs: Get medical advice/attention.

Diethyl malonate | C7H12O4 | CID 7761 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities, safety/hazards/toxicity information, supplier lists, and more.

2024年3月2日 · Chemsrc provides Ethyl malonate (CAS#:145601-68-9) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of Ethyl malonate are included as well.

2024年4月9日 · Character colorless liquid, with a sweet ether odor. solubility miscible with alcohols and ethers, soluble in chloroform, benzene and other organic solvents. Slightly soluble in water. The solubility in water is 2.08g/100ml at 20 °c.