Dec 25, 2024 · ESRRB (Estrogen Related Receptor Beta) is a Protein Coding gene. Diseases associated with ESRRB include Deafness, Autosomal Recessive 35 and Rare Autosomal Recessive Non-Syndromic Sensorineural Deafness Type Dfnb. Among its related pathways are Gene expression (Transcription) and Nuclear receptors.

Estrogen-related receptor beta (ERR-β), also known as ESRRB or NR3B2 (nuclear receptor subfamily 3, group B, member 2), is a nuclear receptor that in humans is encoded by the ESRRB (Estrogen Related Receptor Beta) gene.

雌激素相关受体 b (Esrrb) 是三个孤儿核受体家族的一部分，具有广泛的表达谱和调节哺乳动物能量代谢的通用功能。 然而，Esrrb 在小鼠早期发育、胚胎的多能和多能群体以及原始生殖细胞中执行特定功能。

Apr 27, 2023 · Computational modelling and genomic analyses revealed that ESRRB occupies key formative genes in naive cells and throughout the formative state. In so doing, ESRRB kickstarts the formative...

Estrogen-related receptor b (Esrrb) is part of a family of three orphan nuclear receptors with broad expression profiles and a generic function in regulating energy metabolism in mammals. However, Esrrb performs specific functions during early mouse development, in …

Jul 24, 2015 · Esrrb (oestrogen-related receptor beta) is a transcription factor implicated in embryonic stem (ES) cell self-renewal, yet its knockout causes intrauterine lethality due to...

Aug 23, 2017 · Estrogen-related receptor b (Esrrb) is part of a family of three orphan nuclear receptors with broad expression profiles and a generic function in regulating energy metabolism in mammals.

Jan 28, 2025 · Estrogen related receptor beta (ESRRB) regulates the activity of embryonic stem cell (ESC)-specific enhancer units. The developmentally regulated silencing of ESRRB triggers the selective inactivation of these units within super-enhancers (SEs).

We identified Esrrb, a pluripotency factor that is upregulated during G2/M, as a driver of extraembryonic endoderm stem cell (XEN) differentiation. Furthermore, enhancer chromatin states based on wild-type (WT) and ESRRB knockout (KO) ESCs show association of ESRRB with XEN poised enhancers.

Computational modelling and genomic analyses revealed that ESRRB occupies key formative genes in naive cells and throughout the formative state. In so doing, ESRRB kickstarts the formative transition, leading to timely and unbiased capacity for multi-lineage differentiation.