
ERBB3 - Wikipedia
Receptor tyrosine-protein kinase erbB-3, also known as HER3 (human epidermal growth factor receptor 3), is a membrane bound protein that in humans is encoded by the ERBB3 gene. …
ERBB3 Gene - GeneCards | ERBB3 Protein | ERBB3 Antibody
2024年12月25日 · ERBB3 (Erb-B2 Receptor Tyrosine Kinase 3) is a Protein Coding gene. Diseases associated with ERBB3 include Lethal Congenital Contracture Syndrome 2 and …
ERBB3/HER3:肿瘤治疗新靶点,众多肿瘤驱动基因 研究热点|生物 …
2021年1月15日 · erbb3(又称her3,人表皮生长因子受体3)是表皮生长因子受体家族(egfr)中的一员。erbb3基因位于人类第12号染色体的长臂上(12q13),其编码的蛋白分子量为160 …
什么是酪氨酸激酶受体ErbB3(人表皮生长因子受体3,HER3)?
erbb3是表皮生长因子受体家族 (egfr/erbb)中的一员,和其它egfr家族成员一样,由胞外配体结合域、跨膜结构域和胞内结构域3部分组成。 ErbB3可结合神经调节蛋白配体,但它不能通过蛋白 …
The ERBB3 receptor in cancer and cancer gene therapy - PMC
ERBB3, a member of the epidermal growth factor receptor (EGFR) family, is unique in that its tyrosine kinase domain is functionally defective. It is activated by neuregulins, by other ERBB …
ERBB3 mutations in cancer: biological aspects, prevalence and …
2019年9月13日 · In this review, we discuss the evidence presenting ERBB3 somatic mutations as potential tumoral drivers. We then show that ERBB3 mutations are not uncommon in many …
ERBB3 erb-b2 receptor tyrosine kinase 3 [ (human)]
ErbB3 has a role in cell proliferation in ovarian cancer. HER-3 expression is correlated with better prognosis in neuroendocrine cancer; erbB3 immunoreactivity was prominent in CD133-positive …
ERBB3 mutations in cancer: biological aspects, prevalence and ...
In this review, we discuss the evidence presenting ERBB3 somatic mutations as potential tumoral drivers. We then show that ERBB3 mutations are not uncommon in many cancer types. …
ERBB3 targeting: A promising approach to overcoming cancer …
2024年9月1日 · Using preclinical and clinical evidence, we synthesise and explicate how various aspects of aberrant ERBB3 activities–such as compensatory activation, signal crosstalk …
ErbB信号通路signaling pathway-武汉华美生物
ErbB (erythroblastic oncogene B) belongs to the epidermal growth factor receptor family and consists of an extracellular domain, a transmembrane domain, and a cytoplasmic tyrosine …