EPH receptor A2 (ephrin type-A receptor 2) is a protein that in humans is encoded by the EPHA2 gene. [5][6] This gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase …

2024年11月13日 · In this review, we summarize the main mechanisms underlying EphA2 dysregulation in cancer, highlighting its molecular complexity. Then, we analyze therapies that …

2024年12月25日 · EPHA2 (EPH Receptor A2) is a Protein Coding gene. Diseases associated with EPHA2 include Cataract 6, Multiple Types and Aniridia. Among its related pathways are …

2020年8月18日 · Overall, EphA2 represents a potential target for treating malignant tumors. Ephrin receptors (Eph) represent the most important class of receptor tyrosine kinases (RTKs) …

2020年8月18日 · The tyrosine kinase EphA2, which belongs to the family of Eph receptors, is highly produced in tumor tissues, while found at relatively low levels in most normal adult …

2021年3月8日 · This review will summarize preclinical studies supporting the oncogenic role of EphA2 in breast cancer, lung cancer, glioblastoma, and melanoma, while delineating the …

In this review, we summarize the main mechanisms underlying EphA2 dysregulation in cancer, highlighting its molecular complexity. Then, we analyze therapies that have been developed …

EPHA2 overexpression is associated with poor clinical outcomes; therefore, EPHA2 may represent a promising therapeutic target for patients with NSCLC. In support of this …

Our recent findings has demonstrated that targeting Ephrin Receptor A2 (EPHA2) suppresses HCC initiation and progression by dual inhibition of the Protein Kinase B (AKT) and Signal …

EphA2 Is a Lung Epithelial Cell Receptor for Pneumocystis beta-Glucans. EPHA2 mediates PDGFA activity and functions together with PDGFRA as prognostic marker and therapeutic …