2019年10月22日 · In current clinical practice, procalcitonin (PCT) has developed into a promising new biomarker for the early detection of systemic bacterial infections. PCT is a 116-amino acid residue first explained by Le Moullec et al. in 1984; its …

Procalcitonin is a biomarker produced by the body that is elevated in times of systemic inflammation, particularly when due to bacterial infection. In clinical practice, it can be used to help determine the likelihood of the presence of bacterial infection and guide cessation of antibiotic therapy. 2. Price. Stanford charges $298 for PCT. 3.

Procalcitonin also may be elevated in medullary thyroid cancer, small cell lung cancer, postoperative complications, cirrhosis, pancreatitis, ischemic bowel and paraneoplastic syndrome [8,9].

2024年6月9日 · If your blood contains an abnormally high level of procalcitonin, a substance your body produces in response to a bacterial infection, it can indicate that you have sepsis or are likely to develop sepsis.

Procalcitonin is a serum biomarker that helps distinguish bacterial infection from other causes of infection or inflammation. In patients with lower respiratory tract infections, procalcitonin can serve as a helpful adjunct to clinical judgment for guiding …

Procalcitonin (PCT), regarded as a biomarker specific for bacterial infections, is used in a variety of clinical settings including primary care, emergency department and intensive care. PCT measurement aids in the diagnosis of sepsis and to guide and monitor antibiotic therapy.

Slightly high levels of procalcitonin mean that you are unlikely to develop sepsis, but they may be a sign of: A local bacterial infection, such as a urinary tract infection; An infection from another cause, such as a virus; A systemic bacterial infection that is just beginning

check procalcitonin daily in patients with suspected sepsis; patients with a strong clinical suspicion of sepsis should still be treated as such even if procalcitonin is not initially elevated; serial levels and clinical assessment should be performed over the next few days to determine if antibiotics should be ongoing

Procalcitonin can be elevated in several other disease states, potentially leading to unnecessary antibiotic use in settings outside of respiratory tract infections.

2023年5月4日 · Procalcitonin (PCT), a peptide precursor of the hormone calcitonin, is a biomarker whose serum concentrations are elevated in response to systemic inflammation caused by bacterial infection and sepsis.