ETV6 (i.e. translocation-Ets-leukemia virus) protein is a transcription factor that in humans is encoded by the ETV6 (previously known as TEL) gene. The ETV6 protein regulates the …

Dec 25, 2024 · ETV6 (ETS Variant Transcription Factor 6) is a Protein Coding gene. Diseases associated with ETV6 include Thrombocytopenia 5 and Hematologic Cancer. Among its …

Nov 19, 2020 · ETV6 thrombocytopenia and predisposition to leukemia is a nonsyndromic genetic disorder of thrombocytopenia and high risk of leukemia without any other known congenital …

The ETV6 (also known as TEL) gene encodes a transcriptional repressor that plays a critical role in hematopoiesis and in embryonic development. While somatic ETV6 translocations and …

ETV6-RUNX1（又称TEL-AML1）融合基因，是由12号染色体上的转录因子ETV6基因与21号染色体上的RUNX1序列断裂、重接形成，可影响造血干细胞的自我更新与分化，与白血病的发生 …

Objectives: E26 transformation-specific variant 6 gene (ETV6) is one of the most consistently rearranged genes in acute leukaemia. It encodes a principal hematopoietic transcription factor. …

ETV6 Regulates Hemin-Induced Erythroid Differentiation of K562 Cells through Mediating the Raf/MEK/ERK Pathway. ETV6-NCOA2 fusion induces T/myeloid mixed-phenotype leukemia …

Feb 2, 2023 · etv6(又称tel)基因，位于染色体12p13，编码一种 ets家族 的 转录因子 。etv6基因是一种肿瘤抑制基因，在造血和血管网络发育、维持中起着重要作用。 ETV6基因是一种肿瘤抑 …

该基因的产物包含两个功能域：一个参与蛋白质与自身和其他蛋白质相互作用的 N 末端尖头 (PNT) 域，以及一个 C 末端 DNA 结合域。 小鼠基因敲除研究表明，它是造血作用和维持正在发育 …

Jan 19, 2023 · Here we describe the results of a genome-scale CRISPR–Cas9 screen revealing that the wild-type ETS TF ETS variant 6 (ETV6; also known as TEL) is a crucial Ewing …