
ERK5: structure, regulation and function - PubMed
Extracellular signal-regulated kinase 5 (ERK5), also termed big mitogen-activated protein kinase-1 (BMK1), is the most recently identified member of the mitogen-activated protein kinase …
ERK家族成员 - 百度百科
胞外信号调节激酶 (extracellular signal-regulated kinase,ERK)是MAPK家族的一员,它的信号传递途径是涉及调节细胞生长、发育及分裂的信号网络的核心,其基本的信号传递步骤已明 …
快速了解ERK/MAPK信号通路? - 知乎专栏
在真核细胞中已经确定了以下四条MAPK级联途径:ERK、 JNK 、 p38 MAPK 和ERK5信号转导途径。 今天我们来快速了解一下ERK/MAPK信号通路。 ERK是一种丝氨酸/苏氨酸蛋白激酶,是 …
ERK5信号通路:细胞功能与疾病机制的关键调控者
Jan 3, 2025 · 本文将深入探讨ERK5信号通路的组成、激活机制、生物学功能以及其在疾病中的作用,旨在为研究人员提供对这一领域的全面理解。 ERK5,由816个氨基酸构成,是MAPK家 …
ERK5信号通路研究现状 - 汉斯出版社
摘要: 细胞外信号调节激酶5 (extracellular signal regulated kinase, ERK5)是丝裂原活化蛋白激酶 (mitogen activated protein kinase, MAPK)系统中的重要组成部分,也是MAPK信号转导通路中 …
The MEK5/ERK5 Pathway in Health and Disease - PMC - PubMed …
The MEK5/ERK5 mitogen-activated protein kinases (MAPK) cascade is a unique signaling module activated by both mitogens and stress stimuli, including cytokines, fluid shear stress, …
ERK signalling: a master regulator of cell behaviour, life and fate
Jun 23, 2020 · In this Review, we discuss the current understanding of this important class of kinases. We begin with a brief overview of the structure, regulation, substrate recognition and …
ERK5: Structure, regulation and function - ScienceDirect
Nov 1, 2012 · Extracellular signal-regulated kinase 5 (ERK5), also termed big mitogen-activated protein kinase-1 (BMK1), is the most recently identified member of the mitogen-activated …
Extracellular signal regulated kinase 5 (ERK5) is required for the ...
Sep 9, 2001 · Extracellular signal regulated kinase 5 (ERK5) is a novel member of the mitogen-activated protein kinase (MAPK) family with a poorly defined physiological function. Since …
MAPK家族ERK5信号通路的研究进展 - 百度学术
近年来研究发现,ERK5对细胞的增殖、分化及调节细胞功能有重要作用,并参与一些疾病的发生和发展,故阐明ERK5通路的作用机制,将为一些疾病的诊治提供新的思路与方法。 现重点对ERK5的 …