
EGLN1 - Wikipedia
Hypoxia-inducible factor prolyl hydroxylase 2 (HIF-PH2), or prolyl hydroxylase domain-containing protein 2 (PHD2), is an enzyme encoded by the EGLN1 gene. It is also known as Egl nine …
EGLN1 Gene - GeneCards | EGLN1 Protein | EGLN1 Antibody
2024年12月24日 · EGLN1 (Egl-9 Family Hypoxia Inducible Factor 1) is a Protein Coding gene. Diseases associated with EGLN1 include Erythrocytosis, Familial, 3 and Hemoglobin, High …
EGLN1 gene - MedlinePlus
The EGLN1 gene, often known as PHD2, provides instructions for making an enzyme called prolyl hydroxylase domain 2 (PHD2). The PHD2 enzyme interacts with a protein called hypoxia …
EGLN1 egl-9 family hypoxia inducible factor 1 [ (human)]
2025年2月8日 · findings reveal a differential dependency of clear cell ovarian cancers on EGLN1, thus identifying EGLN1 as a potential therapeutic target in clear cell ovarian cancer patients; …
Oxygen enhances antiviral innate immunity through maintenance of EGLN1 …
2024年4月26日 · EGLN1 is identified as a key mediator of the oxygen enhancement of antiviral innate immune responses. Under sufficient oxygen conditions, EGLN1 retains its prolyl …
Characterization of genetic variants in the EGLN1/PHD2 gene …
We focused our study on the EGLN1 gene and identified 39 germline missense variants including one gene deletion in 47 probands. EGLN1 encodes the PHD2 prolyl 4-hydroxylase, a major …
Entry - *606425 - EGL9 FAMILY HYPOXIA-INDUCIBLE FACTOR 1; EGLN1 …
2020年2月13日 · HGNC Approved Gene Symbol: EGLN1. The EGLN1 gene encodes prolyl hydroxylase domain-containing protein-2 (PHD2), which catalyzes the posttranslational …
EGLN1 egl-9 family hypoxia inducible factor 1
2024年6月17日 · Inhibiting PHD2 in human periodontal ligament cells via lentiviral vector-mediated RNA interference facilitates cell osteogenic differentiation and periodontal repair. An …
EGLN1 egl-9 family hypoxia inducible factor 1 [ Homo sapiens …
2024年11月3日 · Title: A mitochondrial EglN1-AMPKα axis drives breast cancer progression by enhancing metabolic adaptation to hypoxic stress. The ribosomal chaperone NACA recruits …
EGLN1 prolyl hydroxylation of hypoxia-induced transcription …
Egg-laying defective nine 1 (EGLN1) functions as an oxygen sensor to catalyze prolyl hydroxylation of the transcription factor hypoxia-inducible factor-1 α under normoxia …