EO771 is an epithelial-like cell that was isolated from the mammary gland of a patient with carcinoma. This cell line was deposited by R Anderson, Translational Breast Cancer Research Program, Olivia Newton-John Cancer Research Institute. Please fill out the form below to sign up for notification when the product becomes in stock.

The tumor line EO771 is derived from spontaneous breast cancer of C57BL/6 mice. These cells are widely used but are referenced under different names: EO771, EO 771, and E0771. The characteristics of the EO771 cells are well described but some data are contradictory.

2020年7月20日 · Results: The EO771 were estrogen receptor α negative, estrogen receptor β positive, progesterone receptor positive and ErbB2 positive. This phenotype was associated with a sensitivity to anti-estrogen treatments such as tamoxifen, 4 …

EO771, the first luminal B mammary cancer cell line from C57BL/6 mice. EO771, is it a well-characterized cell line for mouse mammary cancer model? Limit and uncertainty.

EO771.LMB cells metastasised spontaneously to lung in C57BL/6 mice and displayed increased invasive capacity compared with parental EO771. By immunohistochemical assessment, EO771 and EO771.LMB were basal-like, as was the 4T1.2 tumour, whereas 67NR had a …

The E0771 cell line is a spontaneously developing medullary breast adenocarcinoma from C57BL/6 mice.[1] Parental E0771 is poorly metastatic when compared to 4T1[2] and has homozygous mutations in the Trp53 and KRAS genes.[3]

2018年6月1日 · E0771 – A Powerful Preclinical Immuno-Oncology Breast Cancer Model. TNBC’s in general are resistant to monotherapy with immunotherapy and are regarded as immunologically “cold” cancers due to their minimal tumor CD8+ T cell infiltrate and low immunogenicity due to a low mutational burden.

2021年10月23日 · E0771 cells significantly induced PD-L1 levels upon IFNγ treatment, which is impaired in E0771 shCdk8–1 and shCdk8–2 knockdown cells (Fig. 6A). These data suggest that regulation of PD-L1 by ...

The tumor line EO771 is derived from spontaneous breast cancer of C57BL/6 mice. These cells are widely used but are referenced under different names: EO771, EO 771, and E0771. The characteristics of the EO771 cells are well described but some data are contradictory.

2020年7月20日 · The EO771 (also named E0771 or EO 771) murine mammary cancer cell line was originally isolated from a spontaneous tumour in C57BL/6 mouse. Although frequently used, this cell line remains poorly characterized. Therefore, the EO771 phenotype was investigated.