Segment polarity protein dishevelled homolog DVL-2 is a protein that in humans is encoded by the DVL2 gene. [5] [6] This gene encodes a member of the dishevelled (dsh) protein family. …

Dec 24, 2024 · DVL2 (Dishevelled Segment Polarity Protein 2) is a Protein Coding gene. Diseases associated with DVL2 include Acyl-Coa Dehydrogenase, Very Long-Chain, …

Disheveled (Dsh) 蛋白（Dvl1、Dvl2 和 Dvl3）抑制糖原合成酶激酶-3β，从而增强 β-连环蛋白的稳定性 。Naked 可通过结合 Dsh 蛋白 并调控平面细胞极性通路的 Dsh 活性，从而抑制典型 …

Jul 6, 2020 · Dishevelled-2 (DVL2) is a central adaptor protein that propagates signals from upstream receptors to downstream effector β-catenin in canonical Wnt signaling.

散乱片段极性蛋白 2： 该基因编码蓬乱 (dsh) 蛋白家族的一个成员。脊椎动物 dsh 蛋白与果蝇 dsh 的氨基酸序列相似性约为 40%。该基因编码一个 90-kD 的蛋白，该蛋白经过翻译后磷酸化形 …

Dvl2 could play a part in epithelial ovarian cancer progression and might be an independent prognostic factor. Additionally, it might be a prospective therapeutic target in the treatment of …

Dec 15, 2022 · Dishvelled-2 (Dvl2) is an essential component of Wnt pathway, which controls several cell fate decisions during development, such as proliferation, survival and …

Feb 20, 2025 · Title: Dvl2 facilitates the coordination of NF-κB and Wnt signaling to promote colitis-associated colorectal progression. Targeting E3 Ubiquitin Ligase WWP1 Prevents …

Dishevelled (Dvl) is a central node of Wnt signaling. Insulin receptor substrates (IRSs), as critical component of insulin signaling, are involved in cell proliferation, metabolism and cancer …

Feb 8, 2025 · Dvl2 mediates a conserved mammalian PCP pathway to regulate convergent extension during neurulation. has a predominant role in mediating Wnt-3a-dependent cell …