2023年6月26日 · Dornase alfa is an inhaled medication that thins mucus, used to manage and treat cystic fibrosis. It has been shown to decrease respiratory tract infections in selected patients with forced vital capacity (FVC) greater than 40% of predicted.

2025年2月1日 · Dornase alfa will not cure cystic fibrosis. However, when it is used every day, it helps make breathing easier and reduces the number of serious lung infections that require treatment with antibiotics. This medicine is available only with your doctor's prescription.

2024年4月1日 · Easy-to-read patient leaflet for Dornase Alfa. Includes indications, proper use, special instructions, precautions, and possible side effects.

Dornase alfa, sold under the brand name Pulmozyme, is used for the treatment of cystic fibrosis. [3] It is a recombinant human deoxyribonuclease I (rhDNase), an enzyme which selectively cleaves DNA. [3] Dornase alfa hydrolyzes the DNA present in sputum/mucus and reduces viscosity in the lungs, promoting improved clearance of secretions. [3]

Dornase alfa is used to reduce the number of lung infections and to improve lung function in patients with cystic fibrosis. It breaks down the thick secretions in the airways, allowing air to flow better and preventing bacteria from building up.

2005年6月13日 · Dornase alfa is a biosynthetic form of human deoxyribunuclease I (DNase I) enzyme. It is produced in genetically modified Chinese hamster ovary (CHO) cells using recombinant DNA technology. The 260-amino acid sequence of dornase alfa is identical to the endogenous human enzyme.

2024年6月28日 · What is dornase alfa? Dornase alfa is used in people with cystic fibrosis to thin mucus in the airways. This may help improve lung function and lower the risk of infections. Dornase alfa may also be used for purposes not listed in this medication guide.

Pulmozyme® (dornase alfa) is a nebulized cystic fibrosis (CF) treatment option to help manage CF symptoms. See full safety for more information.

Find patient medical information for dornase alfa inhalation on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings.

Dornase alfa is a genetically engineered version of a naturally occurring human enzyme which cleaves extracellular deoxyribonucleic acid (DNA). By inhalation of nebulised solution. 2500 units once daily, administered by jet nebuliser, patients over …