DnaG is a bacterial DNA primase and is encoded by the dnaG gene. The enzyme DnaG, and any other DNA primase, synthesizes short strands of RNA known as oligonucleotides during DNA …

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DnaA is the specialist initiator protein that recognizes the origin and guides the formation of these nucleoprotein complexes [92–94]. To initiate DNA replication, this complex must be activated …

2017年4月6日 · To better understand the structure and function of primase and address the interactions between DnaG and specific DNA template, we have carried out structural and …

2019年10月8日 · In E. coli, the hexameric helicase (DnaB), primase (DnaG), single-stranded DNA-binding protein (SSB) and DNA polymerase III holoenzyme (pol III) as the replicative …

Compounds that inhibit bacterial DnaG primase have been developed using different approaches. In this paper, we provide an overview of the current literature on DNA primases as novel drug …

2007年10月19日 · DnaG increases both the NTPase and the helicase activities of DnaB (9), and DnaB both increases and modulates the synthesis of RNA primers by DnaG (1). DnaG …

DnaG is a bacterial DNA primase and is encoded by the dnaG gene. The enzyme DnaG, and any other DNA primase, synthesizes short strands of RNA known as oligonucleotides during DNA …

In Escherichia coli, the primase (DnaG) transcribes ~2000 to 3000 RNA primers per replication cycle5. Biochemical studies have demonstrated that the DnaG primase initiates primer …

The bacterial primase (DnaG)–helicase (DnaB) interaction is mediated by the C-terminal domain of DnaG (p16) and a linker that joins the N- and C-terminal domains (p17 and p33 …