LiverTox - NCBI Bookshelf
4 天之前 · LiverTox ® provides regularly updated, unbiased and easily accessed information on the diagnosis, cause, frequency, clinical patterns and management of liver injury attributable to prescription and nonprescription medications and selected herbal and dietary supplements.
Drug-induced liver injury - UpToDate
This topic will review the epidemiology, clinical manifestations, diagnosis, and management of drug-induced liver injury (DILI). The metabolism of drugs by the liver, the mechanisms by which drugs might injure the liver, and the use of medications in patients with …
Drug-Induced Hepatotoxicity - StatPearls - NCBI Bookshelf
2020年9月19日 · DILI manifests most commonly as jaundice, then weakness, abdominal pain, dark stools or urine, nausea, and pruritis (usually seen in cholestatic liver injury). DILI can present as acute or chronic liver failure, which makes it very difficult to …
Drug-induced Liver Injury - PMC - PubMed Central (PMC)
Drug-induced liver injury (DILI) is common and nearly all classes of medications can cause liver disease. Most cases of DILI are benign, and improve after drug withdrawal. It is important to recognize and remove the offending agent as quickly as ...
Drug-induced liver injury: a comprehensive review - PMC
Drug-induced liver injury (DILI) remains a challenge in clinical practice and is still a diagnosis of exclusion. Although it has a low incidence amongst the general population, DILI accounts for most cases of acute liver failure with a fatality rate of up to 50%.
Drug, Herbal, and Dietary Supplement–induced Liver Injury
This document was developed by consensus of an expert panel and provides guidance statements based on formal review and analysis of the literature on the topics and questions related to the needs of patients with drug and supplement–induced liver injury.
Drug-induced liver injury - PMC - PubMed Central (PMC)
Drug-induced liver injury (DILI) remains the most common cause of acute liver failure (ALF) in the western world. Excluding paracetamol overdose, nearly all DILI encountered in the clinical setting is idiosyncratic in nature because affected ...
DILIN | Drug Induced Liver Injury Network
The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) has established the Drug-Induced Liver Injury Network (DILIN) to collect and analyze cases of severe liver injury caused by prescription drugs, over-the-counter drugs, and alternative medicines, such as herbal products and supplements. Currently, DILIN is conducting 2 ...
Pathology Outlines - Drug / toxin induced hepatitis (DILI)-general
2022年7月21日 · Differential diagnoses include drug induced liver injury, sepsis, shock, paraneoplastic syndrome, intrahepatic cholestasis of pregnancy and familial disorders of bile acid transporter. According to the case note, the patient has …
Drug-Induced Liver Injury Severity and Toxicity (DILIst) Dataset
2023年2月9日 · The drug-induced liver injury severity and toxicity (DILIst) dataset consists of 1,279 drugs that are divided into two classes according to their potential for causing drug-induced...
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