DHX9 Gene - GeneCards | DHX9 Protein | DHX9 Antibody
Dec 24, 2024 · DHX9 (DExH-Box Helicase 9) is a Protein Coding gene. Diseases associated with DHX9 include Intellectual Developmental Disorder, Autosomal Dominant 75 and Werner …
靶向DHX9诱导肿瘤细胞IFN应答和复制应激 - 百度
Jan 29, 2024 · 近日，美国费城肿瘤医院 Israel Canadas 团队在 Cancer Discovery 期刊上发表题为 Targeting DHX9 triggers tumor-intrinsic interferon response and replication stress in Small Cell …
Nature文章揭示DHX9与环状RNA形成的关系 - 搜狐
Apr 6, 2017 · dhx9通过与adar(p150)相互作用，促进这种双链rna结构的解螺旋，微调控基因转录产物的剪接作用和转录后产物的功能。dhx9基因敲除后会大大提高环状rna形成的数目和种类 …
RNA Helicase A - Wikipedia
ATP-dependent RNA helicase A (RHA; also known as DHX9, LKP, and NDHI) is an enzyme that in humans is encoded by the DHX9 gene. [5] [6] [7]
DHX9 maintains epithelial homeostasis by restraining R-loop …
Apr 9, 2024 · Through Dhx9 ΔIEC, Dhx9 ΔPaneth, and Dhx9 iΔISC mice and organoids, we demonstrated that DHX9 is crucial for maintaining intestinal homeostasis. Mechanistically, the …
Nucleic DHX9 cooperates with STAT1 to transcribe interferon
Feb 3, 2023 · In this study, we generated myeloid-specific and hepatocyte-specific DHX9 knockout mice (Dhx9 f/f LysM-Cre and Dhx9 f/f Alb-Cre) and tested the in vivo role of DHX9 in …
RNA damage compartmentalization by DHX9 stress granules
Mar 18, 2024 · Daughter cells arising from UV-exposed mother cells assemble stress granules that are marked by the dsRNA helicase DHX9. These stress granules sequester damaged …
DHX9-dependent recruitment of BRCA1 to RNA promotes DNA end ... - Nature
Jul 5, 2021 · We show that DHX9 plays a critical role in HR by promoting the recruitment of BRCA1 to RNA as part of the RNA Polymerase II transcription complex, where it facilitates the …
Science Advances | 中国科学技术大学朱书等团队合作揭示了DHX9 …
Feb 9, 2023 · dhx9是一种多功能核蛋白，目前尚不清楚它是否在调节细胞核中针对rna病毒的先天免疫中发挥作用。 这项研究表明，DHX9与体内针对RNA病毒感染的先天免疫应答密切相关。
Monoallelic variation in DHX9, the gene encoding the DExH-box …
Aug 3, 2023 · DHX9 encodes a BRCA1-interacting nuclear helicase regulating transcription, R-loops, and homologous recombination and exhibits the highest mutational constraint of all …