2025年2月7日 · a, Dendritic cell (DC)-intrinsic metabolic rewiring during DC maturation in steady state and cancer. The maturation of DCs involves considerable changes in their metabolic …

Dendritic cells are cells of the mononuclear phagocyte system and develop in the bone marrow from common DC precursors that give rise to plasmacytoid DCs (pDCs) and to intermediate …

2024年9月17日 · Dendritic cells (DCs) are crucial gatekeepers of the balance between immunity and tolerance. They exist in two functional states, immature or mature, that refer to an …

2025年1月21日 · We show that cDCs mature by leveraging an internal reservoir of cholesterol (harnessed from extracellular cell debris and generated by de novo synthesis) to assemble …

Dendritic cells (DCs) are specialized antigen-presenting cells that are present at low abundance in the circulation and tissues; they serve as crucial immune sentinels by continually sampling …

The most efficient antigen-presenting cells (APCs) are mature, immunologically competent dendritic cells (DCs). 1-7 DCs are capable of evolving from immature, antigen-capturing cells …

2010年1月15日 · Dendritic cells (DCs) are often produced by granulocyte-macrophage colony-stimulating factor (GM-CSF) and interleukin-4 (IL-4) stimulation of monocytes. To improve the …

2014年5月16日 · In particular, we will highlight the common and distinctive genes and signaling pathways that are associated with the functional maturation of DC subsets. Keywords: …

2014年4月15日 · Dendritic cells are cells of the mononuclear phagocyte system and develop in the bone marrow from common DC precursors that give rise to plasmacytoid DCs (pDCs) and …

Sensing of microbial stimuli causes DCs to enter a complex developmental program called ‘maturation’, which modifies DC morphology and functions profoundly. Maturation enhances …