The expression of DUSP1 gene is induced in human skin fibroblasts by oxidative/heat stress and growth factors. It specifies a protein with structural features similar to members of the non …

2024年12月24日 · DUSP1 (Dual Specificity Phosphatase 1) is a Protein Coding gene. Diseases associated with DUSP1 include Intellectual Developmental Disorder, X-Linked 108 and …

2023年11月7日 · DUSP1 protects against AKI by preventing BAX-induced mtDNA leakage and blocking excessive activation of the cGAS-STING signaling axis through JNK dephosphorylation.

双特异性磷酸酶 1： 该基因编码的蛋白质是一种磷酸酶，对酪氨酸和苏氨酸具有双重特异性。编码的蛋白质可以使 MAP 激酶 MAPK1/ERK2 去磷酸化，从而导致其参与多个细胞过程。这种蛋 …

DUSP1 regulates the JAK2/STAT3 signaling pathway through targeting miR-21 in cervical cancer cells. Extracellular Heat Shock Protein 70 Increases the Glucocorticoid Receptor and Dual …

2021年9月1日 · Particularly, DUSP1 was recognized to negatively regulate immune response by inhibiting pro-inflammatory cytokine production in preceding studies, but it was also found to …

DUSP1 shRNA or nontarget shRNA CAOV3 cells were left untreated or treated with 5µM rapamycin for 20 h prior to being processed for immunofluorescent detection of LC3. Red …

Despite unimpaired insulin signalling and glucose homeostasis, Dusp1 −/− mice were resistant to diet-induced obesity due to increased energy expenditure, but they developed glucose …

2010年10月4日 · Downregulation of DUSP1 induced changes in the expression levels of genes involved in specific biological pathways, including angiogenesis, MAP kinase phosphatase …

2016年5月27日 · 作为苏氨酸-酪氨酸双特异性磷酸酶家族成员的双特异性磷酸酶-1（dusp1 / mkp1），首先在培养的鼠细胞中被发现。 随后通过使用基因敲除小鼠和基因沉默技术的研 …