DNMT1 Gene - GeneCards | DNMT1 Protein | DNMT1 Antibody
2024年12月24日 · DNMT1 (DNA Methyltransferase 1) is a Protein Coding gene. Diseases associated with DNMT1 include Cerebellar Ataxia, Deafness, And Narcolepsy, Autosomal …
DNMT1 - Wikipedia
DNA (cytosine-5)-methyltransferase 1 (Dnmt1) is an enzyme that catalyzes the transfer of methyl groups to specific CpG sites in DNA, a process called DNA methylation. In humans, it is …
不同DNA甲基转移酶DNMT）在癌症发病机制中的作用
2023年2月7日 · 而DNMT1表达水平增加受肿瘤相关巨噬细胞（TAM）调控，DNMT1上调通过肿瘤抑制因子凝溶胶蛋白（Gelsolin）加重GC，而后者介导表观遗传抑制。 先前研究表明， …
Structural basis for activation of DNMT1 - Nature
2022年11月21日 · Nature Communications - DNMT1 is an essential for maintaining genomic DNA methylation. Here, we report the cryo-EM structure of DNMT1 bound to ubiquitinated H3 and …
靶向DNA甲基转移酶DNMT的肿瘤治疗 - 知乎 - 知乎专栏
为了解决甲基化丢失的问题，DNMT1就派上了用场——DNMT1负责准确复制DNA甲基化形式，在DNA复制的过程中起着维持甲基化的作用（如下图所示）；而DNMT3a/3b的作用则是在原本 …
DNMT1 DNA methyltransferase 1 [ (human)] - National Center for ...
DNMT1 regulates miR-20a/TXNIP-mediated pyroptosis of retinal pigment epithelial cells through DNA methylation. DNMT1 expression partially dictates 5-Azacytidine sensitivity and correlates …
DNMT1-Related Disorder - GeneReviews® - NCBI Bookshelf
2012年2月16日 · DNMT1-related disorder is a degenerative disorder of the central and peripheral nervous systems comprising a phenotypic spectrum that includes hereditary sensory and …
Nature|朱冰组首次在体内证实DNMT1可作为起始性DNA甲基转移 …
Nature|朱冰组首次在体内证实DNMT1可作为起始性DNA甲基转移酶，揭示卵子发生过程中DNA甲基化模式建立的机制—专家点评 BioArt生物艺术 科研等 2 个话题下的优秀答主
DNMT1 gene - MedlinePlus
The DNMT1 gene provides instructions for making an enzyme called DNA methyltransferase 1. This enzyme is involved in DNA methylation, which is the addition of methyl groups, consisting …
DNMT1 DNA methyltransferase 1 [ Homo sapiens (human) ]
2025年2月9日 · BAH_Dnmt1_I; BAH, or Bromo Adjacent Homology domain, first copy present in DNA (Cytosine-5)-methyltransferases from Bilateria, Dnmt1 and similar proteins. DNA …