
7-Dehydrocholesterol reductase - Wikipedia
The DHCR7 gene encodes delta-7-sterol reductase (EC 1.3.1.21), the ultimate enzyme of mammalian sterol biosynthesis that converts 7-dehydrocholesterol (7-DHC) to cholesterol. …
DHCR7 Gene - GeneCards | DHCR7 Protein | DHCR7 Antibody
2024年12月24日 · DHCR7 (7-Dehydrocholesterol Reductase) is a Protein Coding gene. Diseases associated with DHCR7 include Smith-Lemli-Opitz Syndrome and Primary Microcephaly. …
DHCR7 gene - MedlinePlus
The DHCR7 gene provides instructions for making an enzyme called 7-dehydrocholesterol reductase. This enzyme is responsible for the final step in cholesterol production in many …
DHCR7: A vital enzyme switch between cholesterol and vitamin …
The conversion of 7-dehydrocholesterol to cholesterol, the final step of cholesterol synthesis in the Kandutsch-Russell pathway, is catalyzed by the enzyme 7-dehydrocholesterol reductase …
Inhibition of 7-dehydrocholesterol reductase prevents hepatic ...
2024年3月12日 · Here, we demonstrate 7-dehydrocholesterol reductase (DHCR7), the terminal enzyme of cholesterol biosynthesis, as a regulator of ferroptosis in hepatocytes. Genetic and …
DHCR7 7-dehydrocholesterol reductase [ (human)] - National …
Inhibition of 7-dehydrocholesterol reductase prevents hepatic ferroptosis under an active state of sterol synthesis. DHCR7 promotes lymph node metastasis in cervical cancer through …
Identification and validation of DHCR7 as a diagnostic biomarker ...
Crucially, DHCR7 was a key EMRG in BC identified and validated by WGCNA, LASSO regression and receiver operating characteristic (ROC) curve analysis. High DHCR7 expression was …
DHCR7 7-dehydrocholesterol reductase - NIH Genetic Testing …
2025年1月4日 · This gene encodes an enzyme that removes the C (7-8) double bond in the B ring of sterols and catalyzes the conversion of 7-dehydrocholesterol to cholesterol. This gene is …
DHCR7 7-dehydrocholesterol reductase [ Homo sapiens (human) ]
2025年2月16日 · Title: DHCR7 promotes lymph node metastasis in cervical cancer through cholesterol reprogramming-mediated activation of the KANK4/PI3K/AKT axis and VEGF-C …
Targeting 7-Dehydrocholesterol Reductase Integrates Cholesterol ...
7-dehydrocholesterol reductase (DHCR7) is an enzyme that catalyzes 7-dehydrocholesterol (7-DHC) to cholesterol, a final step in the biogenesis of cholesterol (Moebius et al., 1998).