
CYR61 - Wikipedia
Cysteine-rich angiogenic inducer 61 (CYR61) or CCN family member 1 (CCN1), is a matricellular protein that in humans is encoded by the CYR61 gene. [5] CYR61 is a secreted, extracellular …
Cysteine-rich 61 (Cyr61): a biomarker reflecting disease activity in ...
Cysteine-rich 61 (Cyr61, also called CCN1), a novel secreted matricellular protein, is encoded by a growth factor-inducible immediate-early gene. Cyr61 expression is at low levels in most adult …
CCN1/CYR61: the very model of a modern matricellular protein
CCN1 (CYR61) is a dynamically expressed, multifunctional matricellular protein that plays essential roles in cardiovascular development during embryogenesis, and regulates …
Cyr61在肿瘤中的作用及临床应用前景 - 中华检验医学杂志
近年研究发现,富含半胱氨酸蛋白61(cysteine-rich 61,Cyr61)在多种肿瘤中异常表达并通过与整联蛋白相结合,促进肿瘤细胞的增殖、增强其侵袭性与抗凋亡能力、参与肿瘤血管生成和肿瘤转 …
Hepatocyte CYR61 polarizes profibrotic macrophages to ... - Science
Sep 27, 2023 · Mooring et al. show that the protein cysteine-rich angiogenic inducer 61 (CYR61) promotes liver-infiltrating macrophage polarization in NASH, leading to inflammation and …
CYR61 - an overview | ScienceDirect Topics
CYR61 (CCN1) is a member of the CCN family of secreted matricellular proteins that functions as a ligand of integrin receptors and BMPs. Cyr61 invalidation shows that this factor is essential …
Regulation of CyR61 expression and release by 3 …
Oct 1, 2022 · We have selected the HCT116 Sh3 CyR61 cell line with the strongest CyR61 downregulation and performed an IncuCyte Scratch Wound Assay and an IncuCyte Cell Count …
Cyr61的研究进展 - 百度学术
Cyr61 (cysteine-rich 61)是结缔组织生长因子 (CCN)家族成员之一,是富含半胱氨酸的分泌性肝素连接蛋白.最初认为是生长因子诱导的即刻早期基因产物,其编码蛋白具有明显的促有丝分裂原性 …
Matricellular protein CCN1/CYR61: a new player in ... - Springer
Mar 18, 2014 · Cystein-rich protein 61 (CYR61/CCN1) is a component of the extracellular matrix, which is produced and secreted by several cell types including endothelial cells, fibroblasts …
Cyr61, a Matricellular Protein, Is Needed for Dendritic Arborization …
Mar 22, 2013 · In this work, we performed a screen for modifiers of dendritic growth in hippocampal neurons, the expression of which is potentially regulated by mTOR. As a result, …