CCR4-NOT transcription complex subunit 7 is a protein that in humans is encoded by the CNOT7 gene. [5][6][7][8] It is a subunit of the CCR4-Not deadenylase complex. The protein encoded …

Dec 24, 2024 · CNOT7 (CCR4-NOT Transcription Complex Subunit 7) is a Protein Coding gene. Among its related pathways are Gene expression (Transcription) and Deadenylation …

Feb 8, 2025 · CNOT7 modulates biological functions of ovarian cancer cells via AKT signaling pathway. Data show that incorporation of ATP-dependent RNA helicase eIF4A-2 (eIF4A2) into …

In this study, we addressed the contribution of CNOT7/8 to viability of primary mouse embryonic fibroblasts (MEFs). We found that MEFs lacking CNOT7/8 expression [Cnot7/8-double …

To examine whether CNOT7/8 catalytic activity is critically involved in MEF viability, we introduced either FLAG epitope-tagged CNOT7-WT or CNOT7 mutants into Cnot7/8-dKO MEFs, using a …

May 20, 2020 · CNOT7 depletion reverses natural killer cell resistance by modulating the tumor immune microenvironment of hepatocellular carcinoma. Ren C, Ren X, Cao D, Zhao H, Zhai …

May 15, 2022 · Depletion of CNOT7 increased CNOT8 incorporation into the CCR4-NOT complex and stabilized CNOT8. These data suggest that CNOT7 is the dominant paralog in CCR4 …

Nov 27, 2024 · Title: CNOT7 modulates biological functions of ovarian cancer cells via AKT signaling pathway. Data show that incorporation of ATP-dependent RNA helicase eIF4A-2 …

McFleder et al. find that CNOT7, the major deadenylase in eukaryotes, has a specialized role in neurons. CNOT7 regulates the dendritic localization and translation of specific mRNAs and …

Jul 10, 2024 · The CNOT7 (CCR4-NOT Transcription Complex Subunit 7) is an important functional subunit of CCR4-NOT protein complex that has not been reported in glioma. In this …