If you’ve been diagnosed with chronic myelomonocytic leukemia (CMML), your treatment team will discuss your options with you. It’s important to weigh the benefits of each treatment option against the possible risks and side effects.

2017年7月13日 · Except for allogeneic stem cell transplantation (ASCT), there is no disease-modifying treatment in CMML. Current therapies aim to improve symptom burden using a personalized strategy guided by cytopenia-induced or proliferation-associated symptoms.

CMML Treatment Options. Our physicians are part of a multidisciplinary leukemia treatment team whose approach to cancer and blood disorders is to personalize the treatment plan for each patient and to treat them holistically, focusing on the whole person and not just on their disease.

2024年9月18日 · Pretreatment evaluation of the patient with chronic myelomonocytic leukemia (CMML) identifies disease-associated symptoms, assesses medical fitness, and evaluates comorbid illnesses to aid selection of a management strategy. Clinical features, initial evaluation and diagnosis, and differential diagnosis of CMML are discussed separately.

For the diagnosis of CMML, the essential methods include peripheral blood tests, bone marrow aspiration and biopsy, chromosomal analysis, and genetic tests. Among them, the morphologic evaluation of peripheral blood and the bone marrow is the basis of CMML diagnosis.

Types of CMML Treatment. In most cases, CMML can't be cured, but it can be treated. Doctors use several types of treatment for adults with CMML, although there's no one standard drug therapy for the disease: Chemotherapy and drug therapy; Stem cell transplantation; Clinical trials ; Finding the Best Treatment Approach. For most CMML patients ...

2024年10月10日 · Chronic myelomonocytic leukemia (CMML) is a chronic type of blood cancer. This means it develops more slowly than acute leukemias. There is currently no cure, but drug treatment, chemotherapy,...

Treatment of CMML depends on how severe the disease is, as well as the patient’s age and health. Treatment options include: Supportive care with blood transfusions, growth factors and antibiotics to treat symptoms by increasing blood counts and stopping infections; Chemotherapy to kill cells cancer cells using cytotoxic agents

Treatments for CMML, especially chemotherapies, destroy the CMML blast cells, but also most of the normal bone marrow cells. In patients with low-risk CMML and MDS features, anaemia can be treated with erythropoiesis stimulating agents to increase the production of red blood cells.

Allogeneic stem cell transplant remains the only potential cure for CMML; however, given the advanced median age at presentation (73 years) and comorbidities, it is an option for only a few affected patients (10%).