CFU-GEMM - Wikipedia
CFU-GEMM is a colony forming unit that generates myeloid cells. CFU-GEMM cells are the oligopotential progenitor cells [1][2] for myeloid cells; they are thus also called common …
四川大学PNAS文章发表新成果 - 生物通
Aug 10, 2012 · 近日来自四川大学、加州大学等处的研究人员发表了题为“Complement factor H genotype impact risk of age-related macular degeneration by interaction with oxidized …
补体因子H关键结构域野生型及突变型克隆载体的构建表达与功能 …
补体因子H(complement factor H，CFH)是补体激活调节蛋白(regulator of complement activation，RCA)基因簇的重要成员之一，CFH基因定位于染色体1q31.3，全长95.4kb，包 …
Variations in the complement regulatory genes factor H (CFH) and …
Deficiency of and mutations in the complement factor H (CFH) gene are associated with the development of MPGN II/DDD, suggesting that dysregulation of the alternative pathway of the …
Understanding Complement Factor H and Macular Degeneration
Jan 2, 2025 · Complement factor H macular degeneration, also known as CFH macular degeneration, is a genetic eye disorder that affects the macula, the central part of the retina. It …
Age-Related Macular Degeneration Associated Complement …
CFH acts as a cofactor for Complement Factor I (CFI) to irreversibly inactivate C3b to iC3b, thereby regulating C3bBb activity as well as enabling opsonin mediated debris clearance …
Cell-autonomous regulation of complement C3 by factor H limits ...
Aug 8, 2023 · Complement factor H (CFH) negatively regulates consumption of complement component 3 (C3), thereby restricting complement activation. Genetic variants in CFH …
Complete functional characterization of disease-associated genetic ...
Jun 22, 2017 · Here we describe a comprehensive procedure to measure levels and functional activity of complement regulator factor H (FH) encoded by CFH, the commonest genetic factor …
补体因子H（CFH）基因家族的周期性结构变异，选择的聚集点和 …
补体因子H（CFH）基因家族的结构变异和单核苷酸变异是几种复杂的遗传疾病的基础，包括年龄相关性黄斑变性（AMD）和非典型溶血性尿毒症综合征（AHUS）。为了了解其多样性和进 …
Entry - *134370 - COMPLEMENT FACTOR H; CFH - OMIM
Complement factor H (CFH), originally known as beta-1H globulin, is a serum glycoprotein that regulates the function of the alternative complement pathway in fluid phase and on cellular …