Cell Fusion: Merging Membranes and Making Muscle - PMC
We focus on three representative types of cell–cell fusion proteins and their respective mechanisms: fusion family (FF) proteins (Caenorhabditis elegans development), fusion-associated small-transmembrane (FAST) proteins (nonenveloped viruses), and myomaker/myomerger (vertebrate myogenesis) .
How cells fuse - PMC - PubMed Central (PMC)
Cell–cell fusion remains the least understood type of membrane fusion process. However, the last few years have brought about major advances in understanding fusion between gametes, myoblasts, macrophages, trophoblasts, epithelial, cancer, and other cells in normal development and in diseases.
Cell Fusion- Types and Significance - Microbe Notes
2022年3月3日 · Cell fusion is an important cellular process in which several uninuclear cells (cells with a single nucleus) combine to form a multinuclear cell, known as a syncytium. Syncytia are commonly found in placenta, bone, cartilage, muscle and multi-nucleated giant cells.
Cell Fusion - Definition, Types, Significance - Biology Notes Online
2024年4月7日 · Cell biologists and biophysicists utilize four strategies to fuse cells. These four methods consist of electrical cell fusion, polyethylene glycol cell fusion, Sendai virus-induced cell fusion, and a recently developed technique known as optically controlled thermoplasmonics.
Biological implications of cell fusion - Nature
2005年6月15日 · This paper shows that cell fusion can contribute to the regeneration of a parenchymal organ and that fusion can eventuate reduction division.
Cell-Cell Fusion: Transient Channels Leading to Plasma …
Below, several cases of developmental cell fusion are surveyed, and we summarize the current knowledge of molecules controlling actual plasma membrane merger and discuss the possibility that the same effect may be brought about by a variety of mechanisms.
How cells fuse | Journal of Cell Biology - Rockefeller University Press
In this review, we discuss the properties and diversity of the known proteins mediating cell–cell fusion and highlight their different working mechanisms in various contexts. The dynamic organization of cells depends on protein-controlled membrane remodeling processes that divide and fuse membranes.
Roles of cell fusion, hybridization and polyploid cell formation in ...
Cell-cell fusion is a normal biological process playing essential roles in organ formation and tissue differentiation, repair and regeneration. Through cell fusion somatic cells undergo rapid nuclear reprogramming and epigenetic modifications to ...
Unveiling the Mechanisms of Cell-Cell Fusion | Science - AAAS
2005年4月15日 · We review advances in understanding cell-cell fusion by contrasting it with virus-cell and intracellular vesicle fusion.
Cell Fusion: Merging Membranes and Making Muscle - Cell Press
2019年10月21日 · Cell fusion is essential for the development of multicellular organisms, and plays a key role in the formation of various cell types and tissues. Recent findings have highlighted the varied protein machinery that drives plasma-membrane merger in different systems, which is characterized by diverse structural and functional elements.
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