CDT1 Gene - GeneCards | CDT1 Protein | CDT1 Antibody
2024年12月24日 · CDT1 (Chromatin Licensing And DNA Replication Factor 1) is a Protein Coding gene. Diseases associated with CDT1 include Meier-Gorlin Syndrome 4 and Meier-Gorlin …
CDT1 gene - MedlinePlus
The CDT1 gene provides instructions for making a protein that is important in the copying of a cell's DNA before the cell divides (a process known as DNA replication). Learn about this gene …
Cdt1 and geminin in DNA replication initiation - PubMed
In this review we summarize structural studies of Cdt1 and Geminin and subsequent insights into how this molecular switch may function to ensure DNA is faithfully replicated only once during …
CDT1 chromatin licensing and DNA replication factor 1 [ (human)]
2025年2月8日 · Cdt1 is phosphorylated and its degradation induced by Cdk2 and Cdk4; human CDT1 is essential for DNA replication and chromatin licensing; Cdt1 overexpression …
Cdt1 and geminin: role during cell cycle progression and DNA ... - PubMed
2007年1月1日 · Cdt1 is regulated over the course of the cell cycle mainly by the controlled expression of an inhibitor protein, geminin, and the level of Cdt1 periodically fluctuates due to …
Regulation and Function of Cdt1; A Key Factor in Cell ... - MDPI
2018年12月3日 · The Cdc10-dependent transcript 1 protein (Cdt1) is required for the first step in DNA replication, and in human cells Cdt1 is also required during mitosis. Tight cell cycle …
Regulation and Function of Cdt1; A Key Factor in Cell ... - PubMed
2016年12月22日 · The Cdc10-dependent transcript 1 protein (Cdt1) is required for the first step in DNA replication, and in human cells Cdt1 is also required during mitosis. Tight cell cycle …
Cdt1 revisited: complex and tight regulation during the cell cycle …
Indeed, Cdt1 overexpression evokes chromosomal damage even without re-replication. Furthermore, deregulated Cdt1 induces chromosomal instability in normal human cells. Since …
Recruitment of the human Cdt1 replication licensing protein by …
2012年5月13日 · In this study, we identify the Cdt1 protein as an essential partner for Ndc80 dynamic function through interaction with the Hec1 loop domain. Cdt1 is required for DNA …
Cdt1 revisited: complex and tight regulation during the cell …
2006年10月17日 · The tight regulation implies that Cdt1 control is especially critical for the regulation of DNA replication in mammalian cells. Indeed, Cdt1 overexpression evokes …
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