Cdk5 is a proline-directed serine/threonine kinase, which was first identified as a CDK family member due to its similar structure to CDC2/CDK1 in humans, a protein that plays a crucial …

The atypical cyclin-dependent kinase 5 (CDK5) is considered as a neuron-specific kinase that plays important roles in many cellular functions including cell motility and survival. The …

2024年12月24日 · CDK5 (Cyclin Dependent Kinase 5) is a Protein Coding gene. Diseases associated with CDK5 include Lissencephaly 7 With Cerebellar Hypoplasia and …

2001年10月1日 · Since it was identified a decade ago, cyclin-dependent kinase 5 (CDK5) has emerged as a crucial regulator of neuronal migration in the developing central nervous system.

Due to the many roles of CDK5 in the development of the nervous system, as well as the effects of cellular stress on CDK5 activation, CDK5 has been implicated in the progression of various …

2021年11月23日 · Cyclin-dependent kinase 5 (Cdk5) is a proline-directed serine/threonine protein kinase. Thirty years ago, Cdk5 was first discovered on the basis of its close sequence …

2024年9月4日 · Here we demonstrate that CDK5 is active during mitosis and is necessary for maintaining mitotic fidelity. CDK5 is an atypical CDK owing to its high expression in post …

2025年1月21日 · Cyclin-dependent kinase 5 (CDK5), a unique member of the CDK family, is a proline-directed serine/threonine protein kinase with critical roles in various physiological and …

2011年12月20日 · Cdk5 is a serine/threonine kinase that is activated upon association with its activator p35 or p39. A predominantly neural-specific kinase because of the restricted …

2025年1月21日 · Cyclin-dependent kinase 5 (CDK5), a unique member of the CDK family, is a proline-directed serine/threonine protein kinase with critical roles in various physiological and …