CD96 is a transmembrane glycoprotein that has three extracellular immunoglobulin-like domains and is expressed by all resting human and mouse NK cells. CD96 main ligand is CD155 . CD …

CD96 is a novel target for cancer immunotherapy shown to regulate NK cell effector function and metastasis. Here, we demonstrated that blocking CD96 suppressed primary tumor growth in a …

2020年7月1日 · CD96 is a promising candidate for immunotherapy. However, its role and importance in glioma remains unknown. We thus aimed to genetically and clinically …

2024年1月19日 · CD96（Cluster of Differentiation 96）是一种细胞表面蛋白，属于Ig超家族的成员之一。 以下是CD96重组蛋白（艾普蒂生物现货目录号：PA1000-6087）的基本信息： 基因 …

CD96 was found to transduce its activating signal through the MEK-ERK pathway. CD96-mediated signaling led to increased frequencies of NUR77- and T-bet-expressing CD8 + T …

2024年12月24日 · CD96 (CD96 Molecule) is a Protein Coding gene. Diseases associated with CD96 include C Syndrome and Developmental And Epileptic Encephalopathy 29. Among its …

Immune checkpoint blockade has become a promising therapeutic approach to reverse immune cell exhaustion. Coinhibitory CD96 and T-cell immunoglobulin and ITIM domain (TIGIT), …

2020年2月11日 · CD96 functions as a co-stimulatory receptor to enhance CD8+ T cell activation and effector responses. CD96 is a member of the poliovirus receptor (PVR, CD155)‐nectin …

2023年1月9日 · Bioinformatics-based analysis of CD96 gene expression in the tissues of patients with hepatocellular carcinoma revealed an increased expression of CD96, suggesting the …

2007年10月3日 · CD96 promoted NK cell adhesion to target cells expressing PVR, stimulated cytotoxicity by activated NK cells, and mediated acquisition of PVR from target cells. Kaname …