
Pathology Outlines - CD10
2023年1月17日 · CD10+ aids in diagnosis but must exclude CD10+ diffuse large B cell lymphoma, Burkitt-like lymphoma with 11q aberration, high grade B cell lymphoma with MYC and BCL2 / BCL6 rearrangement (double / triple hit lymphoma) (75 - 90% CD10+) and B lymphoblastic leukemia / lymphoma (B ALL / LBL) (Am J Clin Pathol 2012;137:665, Am J Clin …
Pathology Outlines - CD10-19
2021年5月11日 · CD Markers - CD10-19. Alpha component of an integrin at 16p11-13.1 that mediates adhesion (OMIM: 120980 [Accessed 10 May 2021])
Pathology Outlines - Endometriosis
2023年11月8日 · CD10 is positive in endometrial stroma ER , PR and PAX2 are often positive in endometrial glands and stroma ( Am J Surg Pathol 2013;37:1342 ) Molecular / cytogenetics description
Pathology Outlines - Stains & CD markers
Kidney: AMACR CAIX CD10 CK7 c-kit / CD117 fumarate hydratase INI1 / SMARCB1 MelanA PAX8 RCC SDHB SMA TFE3 vimentin WT1 Penis: CK5/6 and CK5 HPV p40 p63 Prostate: AMACR androgen receptor (AR) CK5/6 and CK5 ERG NKX3.1 p63 prostein (P501S) PSA PSAP PSMA Testis: AFP CD30 CK7 c-kit / CD117 D2-40 glypican 3 hCG inhibin OCT3/4 PLAP …
Pathology Outlines - Clear cell papillary renal cell tumor
2022年11月21日 · Also has diffuse CAIX but is positive for CD10 and negative or focal for CK7; Loss of chromosome 3p commonly seen Papillary renal cell carcinoma: Clear glycogenated cytoplasm is rare Foamy macrophages and psammoma bodies are common Also usually positive for CK7 but negative or only focal CAIX and often has apical CD10 expression
Pathology Outlines - Renal cell carcinoma (RCC)
2022年2月16日 · A panel of immunohistochemistry stains show tumor cells to be positive for CD10 and RCC Ma, while being negative for CK7, CK20, PAX8, CD117 and CAIX. While the immunohistochemistry profile is not entirely concordant with a renal primary, especially with negative PAX8 and CAIX, the positivity of both CD10 and RCC Ma would suggest possibility of ...
Pathology Outlines - Marginal zone-nodal
2021年9月28日 · Lymphoma cells are CD10 and BCL6 positive and coexpressing BCL2, although monocytoid component could show weak / absent CD10; Additional useful immunostains - HGAL, LMO2 and MEF2B are positive in FL, while MNDA and IRTA1 are positive in NMZL Small lymphocytic lymphoma (SLL): Occasional cases have perifollicular infiltration mimicking NMZL
Pathology Outlines - Follicular-usual
2020年2月26日 · Germinal center markers: CD10, BCL6, HGAL, LMO2. Grade 3B can be more commonly negative CD10 and BCL6 are weaker in interfollicular tumoral cells BCL2 (variable) Positive in 85 - 90% of follicular lymphoma grades 1 and 2 It may be negative in grade 3 False negative: mutations of the BCL2 epitope (anti-BCL2 antibody used)
Dermatofibroma (cutaneous fibrous histiocytoma)
2022年4月11日 · Most useful stain based on evidence is CD163; factor XIIIa is variable in dermatofibroma; CD68 and CD10 are less specific for fibrohistiocytic lineage Ki67 and PHH3 can also be used to show increased proliferation index in dermatofibroma (compared to low index in dermatofibrosarcoma protuberans) (Am J Dermatopathol 2017;39:504)
Pathology Outlines - Eosinophilic vacuolated tumor (EVT)
2025年2月6日 · PAX8, AE1 / AE3, CD10 and antimitochondrial antigens Cathepsin K and CD117 (both may be focal) SDHB and FH retained (positive) References: Mod Pathol 2021;34:1167, Mod Pathol 2022;35:344, Am J Surg Pathol 2022;46:1562