CD20 is a transmembrane protein consisting of four hydrophobic transmembrane domains, one intracellular domain and two extracellular loops. There are three different forms of CD20 …

目前以cd20为靶点的单抗主要分为三代： 第一代就是以强悍疗效而经久不衰的利妥昔及其类似药； 第二代则经过改良的人源化的cd20单抗，但由于其适应症的局限性和抗体结合亲和力的下降， …

Apr 19, 2022 · Learn about the CD20 antigen, where it's found, and how it guides the treatment of lymphomas with monoclonal antibodies.

cd20表达于除浆细胞（分泌免疫球蛋白的b细胞）外的发育分化各阶段的b细胞的表面，通过调节跨膜钙离子流动直接对b细胞起作用，在b细胞增殖和分化中起重要的调节作用。

B淋巴细胞 抗原CD20也称为B淋巴细胞表面抗原B1，白细胞表面抗原Leu-16，跨膜4结构域A成员1和MS4A1，是一种在所有B-细胞表面表达的活化糖基化磷蛋白细胞开始于pro B阶 …

May 7, 2020 · CD20（Cluster of Differentiation 20）是一种跨膜磷蛋白，位于B淋巴细胞表面。 B淋巴细胞是由骨髓内多能干细胞分化而成，其发育经过祖B细胞（Pro-B），前B细胞（Pre …

Anti-CD20 monoclonal antibodies act through several mechanisms, including complement-dependent cytotoxicity (CDC), complement-dependent cellular cytotoxicity (CDCC), antibody …

CD20 is a membrane-embedded surface molecule that is involved in the development and differentiation of B-cells into plasma cells. It is expressed on B-cells throughout their …

Feb 17, 2025 · cd20也是car-t细胞免疫疗法中一个关键的靶点，旨在减轻抗原逃逸风险。靶向cd19和cd20的策略包括双特异性/串联car，cd19和cd20导向的car-t细胞的联合施用，以 …

Sep 20, 2021 · CD20 is a common B cell marker also called L26, membrane spanning 4 domains (MS4A1).