G1/S-specific cyclin-D3 is a protein that in humans is encoded by the CCND3 gene. [5] The protein encoded by this gene belongs to the highly conserved cyclin family, whose members …

2024年12月24日 · CCND3 (Cyclin D3) is a Protein Coding gene. Diseases associated with CCND3 include Thrombocythemia 1 and Leukemia, Acute Lymphoblastic. Among its related …

2022年1月10日 · In this study, we demonstrated that CCND3 is essential for the proliferation and survival of B-ALL, independent of the mutational background. Respectively, its expression at …

2025年2月8日 · CCND3 is the primary driver of the cell cycle, in cooperation with CCND1 that integrates extracellular mitogenic signaling. Observational study of gene-disease association …

By examining human and mouse primary erythroid cells, we demonstrate that the CCND3 gene product cyclin D3 regulates the number of cell divisions that erythroid precursors undergo …

2022年1月10日 · In this study, we demonstrated that CCND3 is essential for the proliferation and survival of B-ALL, independent of the mutational background. Respectively, its expression at …

2018年6月28日 · Here, we show that tightly regulated FOXO1 activity is essential for maintenance of B-cell precursor acute lymphoblastic leukemia (BCP-ALL). Genetic and pharmacological …