The matrix of cartilage acts as a barrier, preventing the entry of lymphocytes or diffusion of immunoglobulins. This property allows for the transplantation of cartilage from one individual to another without fear of tissue rejection.

The cartilage matrix consists of macromolecules in which collagen and proteoglycans (aggrecan) are the main representatives. These components are highly ordered from the cartilage surface to the deepest layers.

Aug 31, 2017 · Formed by the process of chondrogenesis, the resulting chondrocytes are capable of producing large amounts of collagenous extracellular matrix and ground substance, which together form cartilage itself. This article explains the structure, composition, formation and histology of cartilage.

Oct 17, 2022 · The cartilage matrix consists of fibrous tissue and various combinations of proteoglycans and glycosaminoglycans. Cartilage, once synthesized, lacks lymphatic or blood supply, and the movement of waste and nutrition is chiefly done …

Jan 17, 2023 · Cartilage is a flexible connective tissue that differs from bone in several ways. For one, the primary cell types are chondrocytes as opposed to osteocytes. Chondrocytes are first chondroblast cells that produce the collagen extracellular matrix (ECM) and …

Articular cartilage is hyaline cartilage and is 2 to 4 mm thick. Unlike most tissues, articular cartilage does not have blood vessels, nerves, or lymphatics. It is composed of a dense extracellular matrix (ECM) with a sparse distribution of …

Jul 17, 2023 · There are two main cell types in cartilage: The chondroblasts are found near the outer surface of the cartilage, under the perichondrium, and these secrete the extracellular matrix. As they do this, they become entrapped and mature into chondrocytes.

The cartilage matrix comprises a network of collagen fibrils enmeshed in a concentrated PG solution. The collagen and PGs interact to form a porous composite fiber-reinforced organic solid matrix that is swollen with water ( Mow and Hung, 2001).