Caco-2 (from Cancer coli, "colon cancer") is an immortalized cell line of human colorectal adenocarcinoma cells. It is primarily used as a model of the intestinal epithelial barrier. [1] . In …

Caco-2 [Caco2] is an adherent cell line isolated from colon tissue derived from a patient with colorectal adenocarcinoma. These cells express characteristics of enterocytic differentiation …

The human epithelial cell line Caco-2 has been widely used as a model of the intestinal epithelial barrier. The Caco-2 cell line is originally derived from a colon carcinoma. However, one of its …

The Caco-2 cell line derived from human colon carcinoma is commonly used to assess the permeability of compounds in in vitro conditions. Due to the significant increase in permeability …

Although the colonic cell line Caco-2 is widely used as a model of the small intestinal barrier function, it has limitations such as overestimated transepithelial electrical resistance (TEER) …

The Caco-2 cell line is originally derived from a colon carcinoma. However, one of its most advantageous properties is its ability to spontaneously differentiate into a monolayer of cells …

Caco-2, a cell line obtained from human colon adenocarcinoma, is the most well-established intestinal cell model to date. Caco-2 cells differentiate into enterocyte-like cells after 21 days in …

calcium carbonate an insoluble salt occurring naturally in bone, shells, and chalk; used as an antacid, calcium supplement, and phosphate binder, and for treatment of osteoporosis.

The Caco-2 cell line is instrumental in understanding the function and molecular details of intestinal epithelium efflux systems, such as P-glycoprotein, crucial for drug development.

Characterization of the human colon carcinoma cell line (Caco-2) as a model system for intestinal epithelial permeability. Gastroenterology 96:736-749(1989) PubMed= 7764660 ; DOI= …

We tested the culture of Caco-2 cells with human platelet lysate (PL) instead of FCS. We compared cell viability and differentiation by measuring ATP levels, gene and protein …

The human Caco-2 cells differentiate spontaneously in culture forming monolayers of mature intestinal enterocytes which have been used as a model of the intestinal barrier for in vitro …

2022年8月25日 · The Caco-2 monolayer is regarded as an in vitro gold-standard in prediction of intestinal permeability. It finds extensive use in preclinical studies for screening of drugs and …

2024年3月11日 · Caco-2 (human colon adenocarcinoma cells) were isolated from a 72-year-old male with rectal carcinoma in situ. The Caco-2 cell spontaneously differentiates into intestinal …

2022年8月25日 · The Caco-2 cell model has been widely used to assess the permeability of drug candidates. It has provided a high throughput in vitro platform, functionally resembling the …

2021年1月1日 · In brief, compared with the ordinary Caco-2 cell model, the morphology of Caco-2 cells in the 3D model was more similar to normal intestinal cells, and the multidimensional cell …

The human epithelial cell line Caco-2 has been widely used as a model of the intestinal epithelial barrier. The Caco-2 cell line is originally derived from a colon carcinoma. However, one of its …

The Caco-2 cell system, a well characterized intestinal in vitro model, makes it possible to evaluate the ability of chemicals to cross the intestinal barrier, as well as to study their …

5 天之前 · 图1 Caco-2细胞生长正常. 细胞与细胞间紧密连接，一般呈岛状生长，细胞群的边界光滑，细胞群中常常含有巨大的空泡，这是细胞本身的特性，属于正常现象。 图2 Caco-2细胞生 …

2025年2月1日 · In this study, we investigated functional and morphological aspects of Caco-2 cells, alongside their transcriptomic profiles, with a particular emphasis on genes encoding …