Cytochrome P450 2C19 (abbreviated CYP2C19) is an enzyme protein. It is a member of the CYP2C subfamily of the cytochrome P450 mixed-function oxidase system. This subfamily …

The CYP2C19 gene provides instructions for making an enzyme that is found primarily in liver cells in a cell structure called the endoplasmic reticulum, which is involved in protein …

The CYP450 enzyme CYP2C19 is at least partly involved in the metabolism of many drugs, but inhibitors of CYP2C19 will tend to have the greatest effect on drugs for which CYP2C19 is the …

CYP2C19 genotype-guided drug prescribing has been proven in several trials to increase pharmacological effectiveness and safety. For example, CYP2C19 PMs have been observed …

2023年9月1日 · Among the various enzymes responsible for drug metabolism, CYP2C19 stands out as a pivotal player. This article explores the significant role of CYP2C19 in the body, its …

The Pharmacogene Variation Consortium (PharmVar) catalogues star (*) allele nomenclature for the polymorphic human CYP2C19 gene. CYP2C19 genetic variation impacts the metabolism …

2018年1月30日 · CYP2C19 is an enzyme involved in the hydroxylation of the S form of an anti-epileptic agent mephenytoin, and also in the metabolism of a series of proton pump inhibitors …

2024年12月24日 · CYP2C19 (Cytochrome P450 Family 2 Subfamily C Member 19) is a Protein Coding gene. Diseases associated with CYP2C19 include Drug Metabolism, Poor, Cyp2c19 …

2013年7月9日 · CYP2C19 is a member of the IIC subfamily of the cytochrome p450 genes, responsible for metabolizing or activating some hormones (such as estrogens) and several …

2016年10月3日 · Clinical resource with information about CYP2C19, A genome-wide association study of acenocoumarol maintenance dosage., Amitriptyline response, An atlas of genetic …