For drug interaction purposes, the inhibitors and inducers of CYP3A metabolism listed above can alter serum concentrations of drugs that are dependent upon the CYP3A subfamily of liver …

Table of Substrates, Inhibitors and Inducers (including: CYP Enzymes, Clinical index drugs, transporters, and examples of clinical substrates, inhibitors, and inducers).

This is a list of cytochrome P450 modulators, or inhibitors and inducers of cytochrome P450 enzymes.

2022年11月8日 · This article provides a summary of cytochrome P450 enzyme inducers and inhibitors as well as the relevance of genetic polymorphisms which influence metabolic pathways.

2024年6月24日 · Table 2 provides definitions of substrates, inhibitors, and inducers for CYP-based metabolism and Table 3 provides definitions of inhibitors and substrates for drug …

2023年4月24日 · The role of cytochrome P450 (CYP) has been vastly studied for years regarding its influence in drug therapy. Predominantly operating within hepatocytes, their principal …

This review presents a comprehensive update on the inhibitors and inducers of the specific CYP enzymes in humans. The focus is on the more recent human in vitro and in vivo findings since …

2020年10月27日 · The inhibition and induction of CYPs are major mechanisms causing pharmacokinetic drug–drug interactions. This review presents a comprehensive update on the …

CYP3A4 substrates, inhibitors, and inducers commonly used in HCT (non-limitative list) (Lexicomp drug interactions 2023, MedicinesComplete 2023, Stockley’s Interactions Checker)

Human cytochrome P450 (CYP) enzymes, as membrane-bound hemoproteins, play important roles in the detoxification of drugs, cellular metabolism, and homeostasis.