
CXCL10 - Wikipedia
C-X-C motif chemokine ligand 10 (CXCL10) also known as Interferon gamma-induced protein 10 (IP-10) or small-inducible cytokine B10 is an 8.7 kDa protein that in humans is encoded by the CXCL10 gene. [5] [6] C-X-C motif chemokine 10 is a small cytokine belonging to the CXC chemokine family.
CXCL10 Gene - GeneCards | CXL10 Protein | CXL10 Antibody
2024年12月24日 · CXCL10 (C-X-C Motif Chemokine Ligand 10) is a Protein Coding gene. Diseases associated with CXCL10 include Spotted Fever and Cryptosporidiosis. Among its related pathways are MIF Mediated Glucocorticoid Regulation and GPCR downstream signalling.
CXCL10/IP-10 in infectious diseases pathogenesis and potential ...
2020年6月11日 · C-X-C motif chemokine 10 (CXCL10) also known as interferon γ-induced protein 10 kDa (IP-10) or small-inducible cytokine B10 is a cytokine belonging to the CXC chemokine family. CXCL10 binds CXCR3 receptor to induce chemotaxis, apoptosis, cell …
CXCL9, CXCL10, CXCL11/CXCR3 axis for immune activation - a …
CXCL10, known as interferon γ-induced protein 10 (IP-10), is strongly induced by IFN-γ as well as by IFN-α/β and weakly by TNFα.
The emerging role of CXCL10 in cancer (Review) - PMC
In this review, we focus on current research elucidating the emerging role of CXCL10 in the pathogenesis of cancer. Understanding the role of CXCL10 in disease initiation and progression may provide the basis for developing CXCL10 as a potential biomarker and therapeutic target for related human malignancies. 1. Introduction.
CXCL10 - an overview | ScienceDirect Topics
CXCL10, also known as interferon (IFN) γ-inducible protein (IP)−10, is a 8.7 kDa chemokine that has both pro-inflammatory properties and protective physiological functions, including facilitation of angiogenesis and cell-to-cell communication between glia and neurons (Gotsch et al., 2007; Michlmayr and Mckimmie, 2014; Xia et al., 2000).
The role of CXCL family members in different diseases
2023年7月1日 · CXCL10 was also proved to regulate tumor immune microenvironment of ovarian cancer, leading to strong immune cell infiltration. It can activate immune killing response and suppress angiogenesis...
Chemokines beyond chemo-attraction: CXCL10 and its significant ... - PubMed
The current review focuses on a key chemokine named CXCL10 and its role in directing the migratory propertied and biological function of CD4+ and CD8+ T cells in the context of cancer and inflammatory autoimmunity.
Macrophage-Derived CXCL9 and CXCL10 Are Required for …
2020年1月15日 · Results: The CXCR3 ligands, CXCL9 and CXCL10, were significantly upregulated following dual PD-1/CTLA-4 blockade and both CD8 + T-cell infiltration and therapeutic efficacy were CXCR3 dependent.
CXCL10/IP-10 in infectious diseases pathogenesis and potential ...
C–X–C motif chemokine 10 (CXCL10) also known as interferon γ-induced protein 10 kDa (IP-10) or small-inducible cytokine B10 is a cytokine belonging to the CXC chemokine family. CXCL10 binds CXCR3 receptor to induce chemotaxis, apoptosis, cell growth ...