CX3C motif chemokine receptor 1 - Wikipedia
CX3CR1 is integral membrane protein formed by 355 amino acids with molecular weight around 40 kDa, which consist of three distinguishable segments: extracellular, transmembrane and …
Tissue-specific Role of CX3CR1 Expressing Immune Cells and Their ...
Chemokine (C-X3-C motif) ligand 1 (CX3CL1, also known as fractalkine) and its receptor chemokine (C-X3-C motif) receptor 1 (CX3CR1) are widely expressed in immune cells and …
CX3CR1 Gene - GeneCards | CX3C1 Protein | CX3C1 Antibody
Dec 24, 2024 · CX3CR1 (C-X3-C Motif Chemokine Receptor 1) is a Protein Coding gene. Diseases associated with CX3CR1 include Macular Degeneration, Age-Related, 12 and …
T-cell CX3CR1 expression as a dynamic blood-based biomarker of …
Mar 3, 2021 · Here, we investigate CX3C chemokine receptor 1 (CX3CR1), a marker of T-cell differentiation, as a predictive correlate of response to ICI therapy.
The CX3CL1-CX3CR1 chemokine axis can contribute to tumor …
CX3CL1 secreted in the tumor microenvironment serves as a chemoattractant playing a critical role in metastasis of CX3CR1 expressing cancer cells. CX3CR1 can be expressed in both …
Cx3CR1 Expression Identifies Distinct Macrophage Populations …
Jul 1, 2019 · We show Cx3CR1 eGFP-hi macrophages in skin wounds are derived from long-term tissue-resident macrophages and predominantly exhibit an alternative activation state, …
Activation of the human chemokine receptor CX3CR1 regulated …
Jun 29, 2022 · As the only member of the CX3C chemokine receptor subfamily, CX3CR1 binds to its sole endogenous ligand CX3CL1, which shows notable potential as a therapeutic target in …
Structure and Function of Ligand CX3CL1 and its Receptor CX3CR1 …
This review will focus on the unique structural biology features of CX3CL1 and CX3CR1, their interactions in tumour inflammatory response, and antitumour effects, which highlights …
CX3CR1 C-X3-C motif chemokine receptor 1 [ (human)]
CX3CR1 is a potential biomarker of immune microenvironment and prognosis in epithelial ovarian cancer. Validating Fractalkine receptor as a target and identifying candidates for drug …
Generation, Transcriptomic States, and Clinical Relevance of CX3CR1 ...
CX3CR1 was also found to be a marker of T-cell differentiation, where functionally distinct viral and tumor-specific CX3CR1 − CD8 + T cells expressing high levels of TCF-1, CD62L, CD27, …