
CD36, a signaling receptor and fatty acid transporter that …
CD36 is a type 2 cell surface scavenger receptor widely expressed in many immune and non-immune cells. It functions as both a signaling receptor responding to DAMPs and PAMPs, as well as a long chain free fatty acid transporter.
CD36 Gene - GeneCards | CD36 Protein | CD36 Antibody
2024年12月24日 · CD36 (CD36 Molecule (CD36 Blood Group)) is a Protein Coding gene. Diseases associated with CD36 include Platelet Glycoprotein Iv Deficiency and Coronary Heart Disease 7. Among its related pathways are Toll Like Receptor 7/8 (TLR7/8) Cascade and Epigenetic regulation by WDR5-containing histone modifying complexes.
CD36, a Scavenger Receptor Involved in Immunity, Metabolism ...
CD36 is a membrane glycoprotein present on platelets, mononuclear phagocytes, adipocytes, hepatocytes, myocytes, and some epithelia. On microvascular endothelial cells, CD36 is a receptor for thrombospondin-1 and related proteins and functions as a ...
Structure-Function of CD36 and Importance of Fatty Acid Signal ...
CD36 is a scavenger receptor that functions in high affinity tissue uptake of long chain fatty acids (FA) and contributes under excessive fat supply to lipid accumulation and metabolic dysfunction. This review describes recent evidence regarding the ...
CD36 - an overview | ScienceDirect Topics
CD36 is a class B scavenger receptor that binds various ligands such as AGE, oxLDL, fatty acids, collagen, thrombospondin, and anionic phospholipids. It is highly expressed in macrophages and macrophage-derived foam cells in atherosclerotic plaques.
CD36 facilitates fatty acid uptake by dynamic palmitoylation
2020年9月21日 · Restricting CD36 at either palmitoylated or depalmitoylated state eliminates its FA uptake activity, indicating an essential role of dynamic palmitoylation of CD36.
CD36, a Novel Receptor for Oxidized Low-Density Lipoproteins, Is …
1999年5月1日 · We demonstrated that CD36 is expressed on macrophages in atherosclerotic lesions of aorta and that the distributions of CD36-positive and SRA-positive macrophages are different in human atherosclerotic lesions, suggesting the differential contributions of these receptors to foam cell formation.
CD36, a Scavenger Receptor Involved in Immunity, Metabolism
CD36 is a membrane glycoprotein present on platelets, mononuclear phagocytes, adipocytes, hepatocytes, myocytes, and some epithelia. On microvascular endothelial cells, CD36 is a receptor for throm...
The Role of CD36 in Cancer Progression and Its Value as a …
Cluster of differentiation 36 (CD36) is a cell surface scavenger receptor that plays critical roles in many different types of cancer, notably breast, brain, and ovarian cancers. While it is arguably most well-known for its fatty acid uptake ...
CD36: an emerging therapeutic target for cancer and its molecular ...
CD36, a membrane glycoprotein presenting on the surface of cells, binds fatty acids to facilitate their transport for lipid utilization. Upregulated CD36 expression has been observed in multiple cancer types including acute myeloid leukemia, breast cancer, colorectal cancer, gastric cancer, etc.
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