
CD30 - Wikipedia
CD30, also known as TNFRSF8 (TNF receptor superfamily member 8), [5] is a cell membrane protein of the tumor necrosis factor receptor family and a tumor marker. This receptor is …
Pathology Outlines - CD30
CD30, also known as BerH2, Ki1 or TNFRSF8, is a transmembrane glycoprotein receptor that belongs to the tumor necrosis factor receptor (TNFR) and was first identified in Hodgkin …
Understanding CD30 biology and therapeutic targeting: a ... - Nature
Sep 8, 2017 · CD30 is a member of the tumor necrosis factor receptor superfamily. It is characteristically expressed in certain hematopoietic malignancies, including anaplastic large …
The Polyvalent Role of CD30 for Cancer Diagnosis and Treatment
CD30, also known as TNFRSF8 (tumor necrosis factor receptor superfamily member 8), is a protein receptor that is heavily glycosylated inside the Golgi apparatus, as well as a tumor …
CD30: from basic research to cancer therapy - PMC - PubMed …
Cluster determinant 30 (CD30) has been recognized since the 1980s by a monoclonal antibody (Ki-1) as an epitope of a membrane protein highly expressed on Reed–Sternberg and …
CD30 Expression and Its Functions during the Disease Progression …
CD30, a member of the tumor necrosis factor receptor superfamily, plays roles in pro-survival signal induction and cell proliferation in peripheral T-cell lymphoma (PTCL) and adult T-cell …
CD30: expression and function in health and disease - PubMed
CD30 was originally described as a marker of Hodgkin's and Reed-Sternberg cells in Hodgkin's lymphoma. Cloning and characterization of cDNAs encoding CD30 and its ligand (CD30L) …
Diagnostic, prognostic and therapeutic role of CD30 in …
CD30 is a cell surface receptor expressed in classical Hodgkin lymphoma (HL), anaplastic large cell lymphoma (ALCL), and many other lymphomas to a variable degree. It has been identified …
CD30 expression in nonlymphomatous malignancies. | Journal of …
May 20, 2012 · CD30 is the target of brentuximab vedotin (Adcetris), an antibody drug conjugate (ADC) that is approved for the treatment of patients with relapsed HL and systemic ALCL after …
CD30 - an overview | ScienceDirect Topics
CD30 refers to a TNFR-related surface protein that is expressed by activated T and B cells. It was originally identified as a marker for the tumor cells of Hodgkin's lymphoma. CD30 has also …